Following statements are regarding to apoptosis.

A. In the worm apoptotic pathway, CED-3 (caspase-9 in mammals) is a protease required to destroy cell components during apoptosis.

B. CED-4 (Apaf-1) was able to accelerate the autoproteolytic cleavage and activation of purified CED-9

C. Once EGL-1 causes dissociation of the CED-4/CED-9 complex, the released CED-4 dimer joins with three other CED-4 dimers to make an octamer, which then activates CED-3

D. Many apoptotic stimuli lead to damage of the outer mitochondrial membrane, causing release into the cytosol of several proteins that stimulate apoptosis. In particular, cytochrome c released from mitochondria activates Apaf-1, which in turn activates caspase-3 and 7.

Which of the following combination is incorrect?

#Question id: 400

#Unit 1. Molecules and their Interaction Relevant to Biology

Consider two solutions: solution X has a pH of 4; solution Y has a pH of 7. From this information, we can reasonably conclude that ________.

#Question id: 401

#Unit 1. Molecules and their Interaction Relevant to Biology

.Which of the following graphs describes the relationship between [H3O+] and pH?

#Question id: 402

#Unit 1. Molecules and their Interaction Relevant to Biology

If the DG'° of the reaction A -> B is –40 kJ/mol, under standard conditions the reaction:

#Question id: 403

#Unit 1. Molecules and their Interaction Relevant to Biology

For the reaction A -> B, DG'° = –60 kJ/mol.  The reaction is started with 10 mmol of A; no B is initially present.  After 24 hours, analysis reveals the presence of 2 mmol of B, 8 mmol of A. Which is the most likely explanation?

#Question id: 404

#Unit 1. Molecules and their Interaction Relevant to Biology

When a mixture of 3-phosphoglycerate and 2-phosphoglycerate is incubated at 25 °C with phosphoglycerate mutase until equilibrium is reached, the final mixture contains six times as much 2-phosphoglycerate as 3-phosphoglycerate.  Which one of the following statements is most nearly correct, when applied to the reaction as written?  (R = 8.315 J/mol·K; T = 298 K)  3-Phosphoglycerate -> 2-phosphoglycerate

#Question id: 405

#Unit 1. Molecules and their Interaction Relevant to Biology

When a mixture of glucose 6-phosphate and fructose 6-phosphate is incubated with the enzyme phosphohexose isomerase (which catalyzes the interconversion of these two compounds) until equilibrium is reached, the final mixture contains twice as much glucose 6-phosphate as fructose 6-phosphate.  Which one of the following statements is best applied to this reaction outlined below? (R = 8.315 J/mol·K; T = 298 K) Glucose 6-phosphate -> fructose 6-phosphate