For a particular microarray assay (DNA chip), cDNA has been made from the mRNAs of a dozen patients' breast tumor biopsies. Which of the following types of evidence will researchers be looking for in order to determine if the cells are cancerous?

#Question id: 1367

#Unit 4. Cell Communication and Cell Signaling

Match the following junctions (column A) with their intracellular adaptors (column B).

#Question id: 1368

#Unit 4. Cell Communication and Cell Signaling

The following statements are made with reference to the characteristic of proteoglycans (major constituents of ECM). Which one of them is incorrect?

#Question id: 1369

#Unit 4. Cell Communication and Cell Signaling

The following statements are made with reference to characteristics of glycosaminoglycans and proteoglycans, which are major constituents of extracellular matrix. Which one of them is incorrect?

#Question id: 1370

#Unit 4. Cell Communication and Cell Signaling

H. V. Wilson worked with sponges to gain some insight into exactly what was responsible for holding adjacent cells together. He exposed two species of differently pigmented sponges to a chemical that disrupted intercellular junctions, and the cells of the sponges dissociated. Wilson then mixed the cells of the two species and removed the chemical that caused the cells to dissociate. Wilson found that the sponges reassembled into two separate species. The cells from one species did not interact or form associations with the cells of the other species.

How do you explain the results of Wilson's experiments?

#Question id: 1371

#Unit 4. Cell Communication and Cell Signaling

A researcher was studying a protein ‘A’ which has been observed to move across cells when an extracellular electrical stimulus is provided. An artificial peptide ‘Z’ was prepared which resembles the structure of pannexins and competitively inhibits pannexon formation. Which one of the following statements will best explain the fate of protein ‘A’ if, the cells are treated with peptide ‘Z’ and then, electrical stimulus is provided.

#Question id: 1372

#Unit 4. Cell Communication and Cell Signaling

Match the following junctions (Column I) with their functions (Column II).