Transformation of mature cells may also occur due to aberrant expression of stemness genes, resulting in cell clones with a dedifferentiated phenotype and self-renewing capacity resembling stem cells. Recent experimental evidence supporting this proposal has been provided with the induction of adult somatic cells into pluripotent stem (iPS) cells through ectopic expression of four genes encoding the pluripotency factors Oct4 and Sox2, the transcription factor Klf4, and the oncoprotein c-Myc in mouse or human fibroblasts. However, along with pluripotency comes the capability of generating teratomas. On the basis of the above information which of the following outcome is most appropriate?

TLS Online TPP Program

#Question id: 24208

#Unit 1. Molecules and their Interaction Relevant to Biology

What is the true substrate for hexokinase

TLS Online TPP Program

#Question id: 24209

#Unit 1. Molecules and their Interaction Relevant to Biology

Two enzyme having same reaction mechanism using same cofactor such as PDC and KDC

TLS Online TPP Program

#Question id: 24210

#Unit 1. Molecules and their Interaction Relevant to Biology

The human genome encodes four different hexokinases (I to IV), all of which catalyze the same reaction. If Two or more enzymes that catalyze the same reaction but are encoded by different genes are called to be

TLS Online TPP Program

#Question id: 24211

#Unit 1. Molecules and their Interaction Relevant to Biology

Plot of hexokinase IV (Glucokinase) is different While Hexokinases I, II, and III have similar kinetic properties. So, in given graph which of the following represents hexokinase IV and Hexokinases I, II, and III

a. i is representing Hexokinases IV

b. ii is representing Hexokinases I, II, and III

c. i is representing Hexokinases I, II, and III

d. ii is representing Hexokinases IV

Choose the correct option

TLS Online TPP Program

#Question id: 24212

#Unit 1. Molecules and their Interaction Relevant to Biology

Choose the correct statement

a. Hexokinases IV remains sequesters in the nucleus in case of high F-6-P and high ATP

b. Hexokinases IV remains sequesters in the cytoplasm in case of high F-6-P and high ATP

c. Hexokinase requires Mg+2 for its activity, because the true substrate of the enzyme is not ATP4- but the MgATP2- complex.

d. Hexokinase requires Mg+2 for its activity, because the true substrate of the enzyme is MgATP4- but not the MgATP2- complex.

TLS Online TPP Program

#Question id: 24213

#Unit 1. Molecules and their Interaction Relevant to Biology

Choose the incorrect statement