TLS Online TPP Program

#Question id: 1604


Many viruses produce a protein immunoevasin that interferes with antigen presentation by MHC class I molecules. The immunoevasin interfere MHC presentation by

#Unit 4. Cell Communication and Cell Signaling
  1. Block peptide transport to TAP

  2. Inhibiting E3 ubiquitin ligase activity

  3. Block tapasin function

  4. All of the above

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TLS Online TPP Program

#Question id: 41379

#Unit 11. Bioinformatics

What is the main role of NorMD in the described DbClustal workflow?


TLS Online TPP Program

#Question id: 41380

#Unit 11. Bioinformatics

Three protein sequences have the following pairwise evolutionary distances:

Which pair would normally be aligned first in Clustal's progressive alignment procedure?

TLS Online TPP Program

#Question id: 41381

#Unit 11. Bioinformatics

A researcher wants to align protein sequences obtained from a database. The researcher first performs a BLASTP search, identifies conserved local regions and then uses these regions to guide global alignment. 
Which method is most appropriate?


TLS Online TPP Program

#Question id: 41382

#Unit 11. Bioinformatics

Two alignment methods produce different placements for a conserved amino acid. A third method uses an alignment library and checks whether the placement agrees with other alignment evidence. Identify the method.





TLS Online TPP Program

#Question id: 41383

#Unit 11. Bioinformatics

A multiple sequence alignment contains many unrelated or poorly aligned protein sequences. 
Which approach in the described DbClustal workflow can help evaluate the quality of the resulting alignment?

TLS Online TPP Program

#Question id: 41384

#Unit 11. Bioinformatics

Q. Consider the following statements about multiple sequence alignment (MSA).
1.MSA aligns three or more related sequences.
2.MSA can help identify conserved residues and regions.
3.MSA is useful for phylogenetic analysis.
4.MSA is useful only for DNA sequences, not protein sequences.
Which statements are correct?