The titration curve of alanine shows the ionization of two functional groups with pKa values of 2.34 and 9.69, corresponding to the ionization of the carboxyl and the protonated amino groups, respectively. The titration of di-, tri-, and larger oligopeptides of alanine also shows the ionization of only two functional groups, although the experimental pKa values are different. The trend in pKa values is summarized in the table. Which of the following is a reason for this shift in pK values

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#Question id: 32351

#Unit 1. Molecules and their Interaction Relevant to Biology

Compound that have carboxylic acid/phosphoric acid mixed anhydride form

TLS Online TPP Program

#Question id: 32352

#Unit 1. Molecules and their Interaction Relevant to Biology

The net free energy change, DG° of gluconeogenesis for the conversion of Pyruvate to glucose is 

TLS Online TPP Program

#Question id: 32353

#Unit 1. Molecules and their Interaction Relevant to Biology

The principal form in the brain of Hexokinase is 

TLS Online TPP Program

#Question id: 32354

#Unit 1. Molecules and their Interaction Relevant to Biology

In Glucokinase-driven glycolysis

1. ATP/ADP ratio which results in 

2. K⁺ channel opening 

3.  opening of Ca²⁺ channels 

4. secretion of insulin by the b-cells. 

In this way, the action of glucokinase in the b-cells results in glucose uptake.

Choose correct combination of true & false

TLS Online TPP Program

#Question id: 32355

#Unit 1. Molecules and their Interaction Relevant to Biology

Glucose 6-phosphate allosterically inhibits

A) hexokinase I

B) glucokinase

C) hexokinase II

TLS Online TPP Program

#Question id: 32356

#Unit 1. Molecules and their Interaction Relevant to Biology

For given plot of hexokinase

 

a. i is representing Hexokinases IV

b. ii is representing Hexokinases I, II, and III

c. i is representing Hexokinases I, II, and III

d. ii is representing Hexokinases IV

Choose the correct option