TLS Online TPP Program

#Question id: 16953


The ability of any stem cell to self-renew and differentiate depends on the structural organization and cellular function of specialized anatomic microenvironments known as stem cell niches. These sequestered regions are typically populated by a supportive network of stromal cells. Stem cell niche stromal cells express soluble and membrane-bound proteins that regulate cell survival, proliferation, differentiation, and trafficking. Which statements is true about HSCs?

#Unit 4. Cell Communication and Cell Signaling
  1. HSCs are not found in blood
  2. The organs that have microenvironments that support the differentiation of hematopoietic stem cells actually change over the course of embryonic development.
  3. Hematopoietic stem cells actually do not change over the course of embryonic development.
  4. HSCs do not take up residence in the bone marrow, which remains the primary site of hematopoiesis throughout adult life