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TLS Online TPP Program

#Question id: 16958

Plasmacytoma or myeloma tumors secrete large amounts of monoclonal antibodies into the serum and tissue fluids of the patients, and these antibodies can be purified in large quantities. Which statement is true for Bence-Jones proteins?

#Unit 4. Cell Communication and Cell Signaling
  1. tumors will secrete only the light chains, or sometimes both the light chains and the whole antibodies, into the serum. The homogenous light chains secreted by these myeloma tumors are referred to as Bence-Jones proteins.
  2. α and ¥ heavy chains led to further subclassification of these heavy chains into sub-isotypes and their corresponding antibodies.
  3. tumors will secrete only the light chains, or sometimes both the light chains and the whole antibodies, into the serum. The homogenous heavy chains secreted by these myeloma tumors are referred to as Bence-Jones proteins
  4. An antigenic determinant is defined as a region of an antigen that makes cotact with the antigen-combining region on an antibody.
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#Question id: 15255

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