TLS Online TPP Program

#Question id: 18083


The interaction of selection and inbreeding in determining the incidence of autosomal recessive diseases. Consider a gene in which recessive mutations occur at a rate of 10-5. Assume a selective disadvantage S of 0.4 in homozygotes for the recessive allele. Would q be expected to rise, fall, or remain unchanged during the first 10 generations after the cessation of inbreeding, Briefly justify your answer. What numerical value would q approach after thousands of generations with no inbreeding?

#Unit 8. Inheritance Biology
  1. 0.032
  2. 0.00285
  3. 0.0001
  4. 0.005