TLS Online TPP Program

#Question id: 1692


The processing of cytosolic protein involves:

#Unit 4. Cell Communication and Cell Signaling
  1. Transport into late endosomes

  2. Proteasome-mediated cleavage

  3. Displacement of invariant chain

  4. Displacement of β2-microglobulin

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TLS Online TPP Program

#Question id: 5128

#Unit 5. Developmental Biology

During lens formation in the Xenopus, the following statements have been proposed. Which statement is incorrect?

TLS Online TPP Program

#Question id: 5129

#Unit 5. Developmental Biology

once the lens has formed, it induces other tissues. One of these responding tissues is the optic vesicle itself; thus, the inducer becomes the induced. Under the influence of factors secreted by the lens, the optic vesicle becomes the optic cup, and the wall of the optic cup differentiates into two layers: the pigmented retina and the neural retina. such interactions are called as-

TLS Online TPP Program

#Question id: 5130

#Unit 5. Developmental Biology

Regulation by gradients of paracrine factor concentration was elegantly demonstrated by the specification of different mesodermal cell types in the frog Xenopus laevis by activin, a paracrine factor of the TGF-beta family. Which of the following observations are correct from this graph?


TLS Online TPP Program

#Question id: 5131

#Unit 5. Developmental Biology

Differentiated cells express the genes and proteins characteristic of their final identity in the adult, and that identity can be altered only under special circumstances. How does the concept of differentiation, as described here, differ from the concept of determination?

TLS Online TPP Program

#Question id: 5132

#Unit 5. Developmental Biology

Upon secretion of wnt, When Wnt attaches to the Frizzled receptor on a responding cell, the cell secretes Notum, a hydrolase that associates with glypican and then cleaves off Wnt’s attached lipids in a process of deacylation or delipidation. This process:

TLS Online TPP Program

#Question id: 5133

#Unit 5. Developmental Biology

Identify the correct ligands in both receptor serine kinase pathway.