The specificity of antibody secreted by a B-cell may not be the same as that of the surface Ig of the clonal parent because of:

TLS Online TPP Program

#Question id: 33361

#Unit 1. Structure and Function of Biomolecules

a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization

b. Hb Milwaukee: substitutes a Glu for a Val

c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer

d. Hb Philly: substitutes a Phe for a Tyr,

Which Hb variant will not bind to BPG

TLS Online TPP Program

#Question id: 33362

#Unit 1. Structure and Function of Biomolecules

a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization

b. Hb Milwaukee: substitutes a Glu for a Val

c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer

d. Hb Philly: substitutes a Phe for a Tyr

Which Hb variant will have changed pI as compared to HbA

TLS Online TPP Program

#Question id: 33363

#Unit 1. Structure and Function of Biomolecules

An antibody binds to an antigen with a Kd of 5 X10^-8 M. At what concentration of antigen will θ be 0.2

TLS Online TPP Program

#Question id: 33364

#Unit 1. Structure and Function of Biomolecules

An antibody binds to an antigen with a Kd of 5 X10^-8 M. At what concentration of antigen will θ be 0.5

TLS Online TPP Program

#Question id: 33365

#Unit 1. Structure and Function of Biomolecules

An antibody binds to an antigen with a Kd of 5 X10^-8 M. At what concentration of antigen will θ be 0.6

TLS Online TPP Program

#Question id: 33366

#Unit 1. Structure and Function of Biomolecules

An antibody binds to an antigen with a Kd of 5 X10^-8 M. At what concentration of antigen will θ be 0.8