Practice Questions

TLS Online TPP Program

#Question id: 2026

Which of the following statement is FALSE regarding MHC proteins

#Unit 4. Cell Communication and Cell Signaling

MHC class I is a dimer consisting of two chains: one alpha chain (three subunits) and b2 microglobulin chain expressed outside the cell membrane
MHC class I is a dimer consisting of two chains: an alpha and a beta-chain each consisting of two subunits expressed outside the cell membrane
To display a self-peptide in class I and II to maintain tolerance to self-proteins
To display a foreign peptide in class II to show the body is infected and activate TH cells.

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TLS Online TPP Program

#Question id: 28516

#Unit 5. Developmental Biology

The two-experiment performed by a scientist with a forelimb mesenchyme and seeing their results;

I-leg mesenchyme is placed directly beneath the wing AER

II-limb mesenchyme is replaced by non-limb mesenchyme beneath the AER

Conclusion of these experiment are seeing;

a) distal hindlimb structures develop at the end of the limb

b) supernumerary structures are formed, usually toward the distal end of the limb

c) the AER regresses and limb development ceases

Select the correct result about these experiments-

TLS Online TPP Program

#Question id: 28517

#Unit 5. Developmental Biology

What would be the effect of FGFs and Wnts treatment on the ‘bone formation’ of young limb bud mesenchyme?

TLS Online TPP Program

#Question id: 28518

#Unit 5. Developmental Biology

Achondroplasia is caused by base-pair substitution mutation that converts ____

TLS Online TPP Program

#Question id: 28519

#Unit 5. Developmental Biology

A Condition wherein chondrocytes stop proliferating earlier than usual, resulting in short limbs, that causes

TLS Online TPP Program

#Question id: 28520

#Unit 5. Developmental Biology

Thanatophoric dysplasia is caused by the mutation in which of the following;

a) base-pair substitution that converts glycine to arginine

b) extracellular domain of the FgfR3 protein

c) transmembrane domain of the FgfR3 protein

d) tyrosine kinase intracellular domain of the FgfR3 protein

TLS Online TPP Program

#Question id: 28521

#Unit 5. Developmental Biology

Which of the following stage of the diploid life cycle commences with the fusion of the haploid egg and sperm to form the single-celled ?