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TLS Online TPP Program
#Question id: 7545
#General Aptitude
How long a train 150 meters long running at the speed of 108km/hr take to cross a bridge 186 meters in length?
TLS Online TPP Program
#Question id: 28483
#Unit 5. Developmental Biology
In ICM cells, which of the following protein phosphorylates Yap and gets degraded ?
TLS Online TPP Program
#Question id: 7048
#Unit 5. Developmental Biology
During the specification of neural crest cells, the neural plate is bordered by neural crest anteriorly and caudally, and by placodal ectoderm anteriorly. If the ectodermal cells receive both BMP and Wnt for an extended period of time, they become
TLS Online TPP Program
#Question id: 3812
#Unit 3. Fundamental Processes
The mechanism of DNA replication is studied in an E. coli replication fork. Which is a characteristic of this replication fork?
TLS Online TPP Program
#Question id: 16126
#Unit 13. Methods in Biology
2 You are studying regulation of the yeast enzyme glutamine synthetase (GS), which is encoded by the GLN1 gene. You have isolated two mutants, designated gln2– and gln3–, that give decreased GS activity. Mating of either gln2– or gln3– haploids to wild type produces heterozygous diploids that show normal amounts of GS expression. When you cross either a gln2– or gln3– haploid to a gln1– strain the resulting diploids show normal expression of GS, that could explain the effect of the gln2– and gln3– mutations on the regulation of GLN1.
The GLN1 gene shows a rather complex regulation in response to different amino acids. When either glutamate (glu) or glutamine (gln) is added to the medium, the amount of GS expression diminished and when both glutamate and glutamine are added to the medium GS expression is shut off completely. The effects of different mutants on the response to glu and gln are shown below.
