Practice Questions

  1. Home
  2. Free Resources
  3. Practice Questions
  4. 20218
TLS Online TPP Program

#Question id: 18928

With respect to nucleic acid hybridization, which, if any, of the following statements is false?

#Unit 13. Methods in Biology
  1. The probe is a labeled nucleic acid or oligonucleotide that is expected to hybridize to a target DNA sequence within an unlabelled test nucleic acid population.
  2. The probe is a known single-stranded nucleic acid or oligonucleotide that is intended to hybridize to complementary target sequences in a poorly understood nucleic acid test sample.
  3. The object of a hybridization assay is to identify target sequences within a test sample that are related to the probe so that some new information is gained about the target sequences.
  4. During a hybridization assay, a heteroduplex is formed by un-natural base pairing between complementary probe and target sequences that show a sufficiently high degree of base pairing across part or all of their lengths.
More Questions
TLS Online TPP Program

#Question id: 34111

#Unit 2. Cellular Organization

A. 11-nm chromatin fibers consist of a string of nucleosomes.
B. 30-nm fibers have six nucleosomes/turn, which are organized into a two-start helix.
C. Histone H1, histone tails, and increased ionic strength all promote the formation of the 11-nm fiber.
D. Histone octamers are well conserved during replication, with H2A-H2B dimers and H32-H42 tetramers are.

Which of the correct combination of statements
TLS Online TPP Program

#Question id: 34112

#Unit 2. Cellular Organization

A. When interphase nuclei are suspended in a solution of low ionic strength, they swell and rupture to release fibers of chromatin.
B. Individual nucleosomes can be obtained by treating chromatin with the endonuclease micrococcal nuclease
C. When chromatin is digested with MNase, the DNA is cleaved into integral multiples of a unit length can be Fractionated by gel electrophoresis reveals the “ladder”
D. With MNase more than 95% of nuclear DNA can be recovered in the form of the 200-bp ladder.

Choose true and false
TLS Online TPP Program

#Question id: 34113

#Unit 2. Cellular Organization

Which of the following is incorrect statement 
TLS Online TPP Program

#Question id: 34114

#Unit 2. Cellular Organization

The tail of which histone/s is able to contact an H2A-H2B dimer in an adjacent nucleosome, which may contribute to the formation of higher order structures
TLS Online TPP Program

#Question id: 34115

#Unit 2. Cellular Organization

Choose correct statement
TLS Online TPP Program

#Question id: 34116

#Unit 2. Cellular Organization

A. The positive charge on lysine is neutralized upon acetylation
B. Methylated lysine and arginine are neutral.
C. Lysine can be mono-, di-, or triacetylated
D. Arginine can be mono or diacetylated. 
E. Both Lysine and Arg can be acetylated

Choose true and false