#Question id: 1536
#Unit 4. Cell Communication and Cell Signaling
Use the following figure to answer the question. According to figure, which of the following statement is incorrect?
#Question id: 1537
#Unit 4. Cell Communication and Cell Signaling
Transformation of mature cells may also occur due to aberrant expression of stemness genes, resulting in cell clones with a dedifferentiated phenotype and self-renewing capacity resembling stem cells. Recent experimental evidence supporting this proposal has been provided with the induction of adult somatic cells into pluripotent stem (iPS) cells through ectopic expression of four genes encoding the pluripotency factors Oct4 and Sox2, the transcription factor Klf4, and the oncoprotein c-Myc in mouse or human fibroblasts. However, along with pluripotency comes the capability of generating teratomas. On the basis of the above information which of the following outcome is most appropriate?
#Question id: 1538
#Unit 4. Cell Communication and Cell Signaling
Many aspects of the biology of stem cells, including maintenance of pluripotency, self-renewal, and differentiation, are controlled by the phenomenon of RNA interference involving a variety of small molecules of RNA.
Match the following miRNA (Column I) with their target gene (Column II).
Column I |
Column II |
a. Let-7 miRNA |
i. Bcl-2 |
b. miR-16 |
ii. PTEN phosphatase |
c. miR-125a and miR-125b |
iii. Myc |
d. miR-21 |
iv. LIN28 |
#Question id: 15303
#Unit 4. Cell Communication and Cell Signaling
#Question id: 15304
#Unit 4. Cell Communication and Cell Signaling
#Question id: 15305
#Unit 4. Cell Communication and Cell Signaling