Consider the ABO “blood type” gene. This single gene has three alleles called A, B, and O. There are four resultant “blood types” (phenotypic classes), as follows:

                             

Assume Hardy-Weinberg equilibrium, the frequencies of the A and B alleles are 0.26 and 0.07, respectively. You now examine the ABO blood types in yet another population. You observe that the AB blood type has a frequency of 0.50 in this population. What are the frequencies of the A and O alleles in this population?

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#Question id: 12484

#Unit 2. Cellular Organization

Match the following.

Column I	Column II
A. APC/CCdc20	i . responsible for ubiquitinating proteins, such as mitotic cyclins
B. APC/CCdh1	ii. responsible for destroying proteins, such as securin
	iii. promotes the metaphase–anaphase transition
	iv. Promotes exit from mitosis

Which of the following is correct?

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#Question id: 12485

#Unit 2. Cellular Organization

Following statements are regarding to the centrosome cycle of an animal cell.

A. During G1, the daughter procentrioles continue to elongate.

B. During S phase, daughter procentrioles form adjacent to maternal centrioles so that two pairs of centrioles become visible within the centrosome. 

C. During G2 phase, the centrosome contains a single pair of centrioles.

D. At the beginning of mitosis, the centrosome splits, with each pair of centrioles becoming part of its own centrosome. As they separate, the centrosomes organize the microtubule fibres that make up the mitotic spindle.

Which of the following option is correct? 

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#Question id: 12486

#Unit 2. Cellular Organization

Which of the following process occur in prometaphase?

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#Question id: 12487

#Unit 8. Inheritance Biology

Neurofibromatosis type 1 is one of the most common autosomal dominant disorders. A woman with neurofibromatosis type 1 has an unaffected partner. Which of the following is correct regarding their children?

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#Question id: 12488

#Unit 8. Inheritance Biology

Retinoblastoma usually occurs as a sporadic event but in around 10% of cases there is a positive family history due to autosomal dominant inheritance. In these families the penetrance is approximately 80% (= 0.8). A woman with retinoblastoma, whose father and grandfather were also affected, has an unaffected partner with no relevant family history. Which of the following is correct regarding their children?

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#Question id: 12489

#Unit 8. Inheritance Biology

Achondroplasia shows autosomal dominant inheritance with complete penetrance. A man with achondroplasia has an unaffected partner of normal height. Their first two children are not affected. Which of the following is correct?