TLS Online TPP Program

#Question id: 2058


NOD-like receptors (NLRs) are a large family of cytosolic PRRs activated by intracellular PAMPs, DAMPs, and other harmful substances. The NOD NLRs bind intracellular microbial components such as cell wall fragments. NLRC family are NOD1 and NOD2 recognise?

#Unit 4. Cell Communication and Cell Signaling
  1. NOD1- Trypanosoma cruzi, NOD2- influenza

  2. NOD1- influenza, NOD2- Trypanosoma cruzi

  3. NOD1 & NOD2- Trypanosoma cruzi

  4. NOD1 & NOD2- influenza

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TLS Online TPP Program

#Question id: 5351

#Unit 8. Inheritance Biology

Consider the accompanying pedigree of a rare autosomal recessive disease, PKU. (Assume individual coming from outside that is homozygous for normal allele) What is the probability of child showing trait of A and B individuals?

TLS Online TPP Program

#Question id: 5352

#Unit 8. Inheritance Biology

Marriage occurs between individuals III-3 and III-6, what is the probability couple; son would be affected with the trait?

TLS Online TPP Program

#Question id: 5353

#Unit 8. Inheritance Biology

Which of following is not a mode of inheritance, but female parents (I-1) carry only normal allele?

A. X link recessive              b. Autosomal recessive

c. Autosomal dominant      d. X- link dominant

TLS Online TPP Program

#Question id: 5354

#Unit 8. Inheritance Biology

Eye color gene link with X chromosome, If red eye color gene is dominant over white eye color gene. Which of the following genetic cross and their respective offspring is not correlated?

Genetic cross

Phenotype of offspring

1

Heterozygous Red eye female  X   Red eye Male

All male red eye

2

Heterozygous Red eye female  X   white  eye Male 

 Male either red  or white eye

3

Homozygous Red eye female  X   white eye Male 

All female red eye

4

Homozygous Red eye female  X   Red  eye Male

All male red eye

TLS Online TPP Program

#Question id: 5355

#Unit 8. Inheritance Biology

The characteristics of X-linked inheritance as following statement are correct

A- Reciprocal crosses resulting in different phenotypic ratios in their offspring 

B- Heterozygous females transmit each X-linked allele to approximately half their daughters and half their sons

C- Males that inherit an X-linked recessive allele always exhibit the recessive trait

D-Females that inherit an X-linked recessive allele from male always exhibit the dominant trait

E- Males do not transmit each X-linked allele to their sons

TLS Online TPP Program

#Question id: 5356

#Unit 8. Inheritance Biology

In the following pedigree, individuals with shaded circle or shaded square show presence of a recessive autosomal trait. The calculated risk of occurrence of this trait for III-I is