TLS Online TPP Program

#Question id: 19107


Assume that mating is random. First, consider an autosomal recessive disease that is usually lethal in childhood, and that has an incidence among newborns of 1/3000.  Perhaps the explanation for the incidence of the disease is heterozygote advantage. How large would this heterozygote advantage have to be (assuming the mutation rate is negligible)? 

#Unit 8. Inheritance Biology
  1. 3.33%
  2. 5.40%
  3. 1.83%
  4. 2.65%
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TLS Online TPP Program

#Question id: 2237

#Unit 2. Cellular Organization

Glucose enters erythrocytes via a GLUT-1 uniporter. As the levels of glucose in the bloodstream decrease between meals, what happens to the glucose in the cells?

TLS Online TPP Program

#Question id: 2238

#Unit 2. Cellular Organization

Consider the transport of glucose into an erythrocyte by facilitated diffusion.  When the glucose concentrations are 5 mM on the outside and 0.1 mM on the inside, the free-energy change for glucose uptake into the cell is:  (These values may be of use to you:  R = 8.315 J/mol·K; T = 298 K; 9 (Faraday constant) = 96,480 J/V; N = 6.022×10²³ /mol.)

TLS Online TPP Program

#Question id: 2239

#Unit 2. Cellular Organization

Consider the transport of K+ from the blood (where its concentration is about 4 mM) into an erythrocyte that contains 150 mM K+.  The transmembrane potential is about 60 mV, inside negative relative to outside.  The free-energy change for this transport process is:  (These values may be of use to you:  R = 8.315 J/mol.K; T = 298 K; 9 (Faraday constant) = 96,480 J/V; N = 6.022×10²³ /mol.)

TLS Online TPP Program

#Question id: 2240

#Unit 2. Cellular Organization

 In which of the following cases is energy NOT needed for transmembrane transport?

a. Lysine moves into the cell against its concentration gradient via the Na+/lysine symporter.

b. Potassium ions (K+) move out of the cell down the K+ concentration gradient via potassium channels.

c. Glucose moves into the cell down its concentration gradient via a glucose uniporter.

d. Sodium ions (Na+) move out of the cell down the Na+ concentration gradient via sodium channels.

Which of the following are correct?

TLS Online TPP Program

#Question id: 2241

#Unit 2. Cellular Organization

Which of the following statement(s) is (are) true of V-class proton pumps?

TLS Online TPP Program

#Question id: 2242

#Unit 2. Cellular Organization

What two features of the structure of cholesterol make it somewhat amphipathic?