You are conducting genetic linkage studies of an autosomal recessive disease whose chromosomal location has not been firmly established. You are focused on two SSR markers that may be linked to each other and to the disease. Here are two families in which some individuals are affected:

                

Calculate LOD scores for linkage at θ= 0.02 between the disease and SSR43 in Family 1.

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#Question id: 14504

#Unit 13. Methods in Biology

If the probability of a defective bolt is 0.1, the mean and standard deviation for the distribution of defective bolts in a total of 500 are

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#Question id: 14505

#Unit 13. Methods in Biology

Two cards are drawn with replacement from a well shuffled deck of 52 cards. The mean and standard deviation for the number of aces are

Probability distribution table

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#Question id: 14506

#Unit 13. Methods in Biology

In a Binomial distribution, the mean and standard deviation are 12 and 2 respectively. The values of n and p are respectively.

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#Question id: 14507

#Unit 13. Methods in Biology

For a biased die the probabilities for different faces to turn up are given below.

The die is tossed and you are told that either face 1 or face 2 has turned up. The probability that it is face 1 is

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#Question id: 14508

#Unit 13. Methods in Biology

There are three events A, B and C, one of which must occur and only one can happen, the odds are 8 to 3 against A, 5 to 2 against B; find the probability of C.

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#Question id: 14509

#Unit 13. Methods in Biology

Aishwarya studies either computer science or mathematics everyday. If she studies computer science on a day, then the probability that she studies mathematics the next day is 0.6. If she studies mathematics on a day, then the probability that she studies computer science the next day is 0.4. Given that Aishwarya studies computer science on Monday, what is the probability that she studies computer science on Wednesday ?