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TLS Online TPP Program
#Question id: 12185
#Unit 2. Cellular Organization
Mitotic CDKs affect nuclear envelope components by specific mechanism. Which of the following statement is not related to this mechanism?
TLS Online TPP Program
#Question id: 12186
#Unit 2. Cellular Organization
In 2001, the Nobel Prize in Physiology or Medicine was awarded to three cell cycle scientists. Paul Nurse was recognized for his studies with the fission yeast S. pombe, in particular for the discovery and characterization of the wee1+ gene. What did the characterization of the wee1+ gene tell us about cell cycle control?
TLS Online TPP Program
#Question id: 12187
#Unit 2. Cellular Organization
How cells know whether sister kinetochores are properly attached to the mitotic spindle?
TLS Online TPP Program
#Question id: 12188
#Unit 2. Cellular Organization
The series of events by which APC/C promotes the separation of sister chromatids at anaphase.
A. all the kinetochores have attached to spindle microtubules and the spindle apparatus is properly assembled and oriented.
B. Cdc20 specificity factor associated with APC/C directs it to ubiquitinylate securin and mitotic cyclins.
C. A protease known as separase cleaves the cohesin subunit Scc1 (Rad21), breaking the protein circles linking sister chromatids.
D. anaphase begins as poleward force exerted on the kinetochores moves the split sister chromatids toward opposite spindle poles.
E. Following securin degradation and a decrease in mitotic CDK activity.
Which of the following series is correct?
TLS Online TPP Program
#Question id: 12189
#Unit 2. Cellular Organization
Following statements are regarding to model for reassembly of the nuclear envelope during telophase.
A. Extensions of the endoplasmic reticulum (ER) associate with each decondensing chromosome and then fuse with one another, forming a double membrane around the chromosome.
B. Dephosphorylated nuclear pore subcomplexes reassemble into nuclear pores, forming individual mini-nuclei called karyomeres.
C. The enclosed chromosome further decondenses, and subsequent fusion of the nuclear envelopes of all the karyomeres at each spindle pole forms a single nucleus containing a full set of chromosomes.
D. Phosphorylated nuclear pore subcomplexes reassemble into nuclear pores, forming individual mini-nuclei called karyomeres.
Which of the following is incorrect?
TLS Online TPP Program
#Question id: 12190
#Unit 2. Cellular Organization
CDK activity is modulated by the following proteins:
(a) cyclin, (b) CAK, (c) Wee1, (d) p21. Following protein act as:
I. Inhibitory kinase
II. CKI Family of proteins
III. Activatory kinase
IV. Regulatory subunit
Which of the following is correct?