A research team is working on the design of a new drug for the treatment of lung cancer. To be most effective, this drug must specifically enter the cytoplasm of lung cells while not entering the cells of other tissues. Which of the following characteristics would likely enhance the specificity of this drug?

TLS Online TPP Program

#Question id: 32352

#Unit 1. Molecules and their Interaction Relevant to Biology

The net free energy change, DG° of gluconeogenesis for the conversion of Pyruvate to glucose is 

TLS Online TPP Program

#Question id: 32353

#Unit 1. Molecules and their Interaction Relevant to Biology

The principal form in the brain of Hexokinase is 

TLS Online TPP Program

#Question id: 32354

#Unit 1. Molecules and their Interaction Relevant to Biology

In Glucokinase-driven glycolysis

1. ATP/ADP ratio which results in 

2. K⁺ channel opening 

3.  opening of Ca²⁺ channels 

4. secretion of insulin by the b-cells. 

In this way, the action of glucokinase in the b-cells results in glucose uptake.

Choose correct combination of true & false

TLS Online TPP Program

#Question id: 32355

#Unit 1. Molecules and their Interaction Relevant to Biology

Glucose 6-phosphate allosterically inhibits

A) hexokinase I

B) glucokinase

C) hexokinase II

TLS Online TPP Program

#Question id: 32356

#Unit 1. Molecules and their Interaction Relevant to Biology

For given plot of hexokinase

 

a. i is representing Hexokinases IV

b. ii is representing Hexokinases I, II, and III

c. i is representing Hexokinases I, II, and III

d. ii is representing Hexokinases IV

Choose the correct option

TLS Online TPP Program

#Question id: 32357

#Unit 1. Molecules and their Interaction Relevant to Biology

There are two classes of aldolases such as;

A) Class I aldolases B) Class II aldolases

i) Found in animals and plants

ii) Found in fungi and bacteria

iii) formation of protonated Schiff base on enzyme and its active site contain lysine residue

iv) do not form the Schiff base intermediate and a zinc ion at the active site is coordinated with the carbonyl oxygen at C-2

In which of the following option is the given enzyme with its correct statements?