The processing and repair of DSBs can lead to 

TLS Online TPP Program

#Question id: 258

#Unit 1. Molecules and their Interaction Relevant to Biology

 It is easier to melt DNA richer in AT than GC because

TLS Online TPP Program

#Question id: 799

#Unit 1. Molecules and their Interaction Relevant to Biology

The two cleavage reactions required to generate the miRNA from these primary transcripts are mediated by two distinct RNases. A characteristic of both these enzymes is that they recognize and cleave RNAs on the basis of the structure of their substrates rather than their specific sequence. Which of the following statement is INCORRECT regarding the cleavage reactions that produces a mature RNA?

TLS Online TPP Program

#Question id: 744

#Unit 1. Molecules and their Interaction Relevant to Biology

In a DNA molecule, deoxyribonucleotides are joined into a polymer by the covalent linkage of a phosphate group. The covalent link termed as:

TLS Online TPP Program

#Question id: 15152

#Unit 8. Inheritance Biology

In this problem we will explore some of the many ways that mutations in two different genes can interact to produce different Mendelian ratios. Consider a hypothetical insect species that has red eyes. Imagine mutations in two different unlinked genes that can, in certain combinations, block the formation of red eye pigment yielding mutants with white eyes. In principle, there are two different possible arrangements for two biochemical steps responsible for the formation of red eye pigment. The two genes might act in series such that a mutation in either gene would block the formation of red pigment. Alternatively, the two genes could act in parallel such that mutations in both genes would be required to block the formation of red pigment.

Further complexity arises from the possibility that mutations in either gene that lead to a block in enzymatic activity could be either dominant or recessive. If the crosses is made between a wild type insect with red eyes and a true breeding white eyed strain with mutations in both genes. Such considerations yield the Pathways in series with dominant mutations in both genes, determine the phenotype of the F1 progeny and the expected phenotypic ratio of red to white eyed insects in the F2.

TLS Online TPP Program

#Question id: 33907

#Unit 2. Cellular Organization

A circular DNA molecule with 580,070 bp. Calculate the molecular weight and contour length (when relaxed) of this molecule. What is Lko for the Mycoplasma chromosome? If σ=-  0.06, what is Lk?