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TLS Online TPP Program

#Question id: 2250

Which of the following is true about cystic fibrosis?

#Unit 2. Cellular Organization

  1. The normal CFTR channel protein is a chloride uniporter, but CF patients have a mutation that makes it require ATP.

  2.  CFTR mutations result in a mutated protein, which pumps too many chloride ions out of the cell.

  3. There are no treatments for patients with CF that are specifically targeted to the CFTR receptor.

  4. Patients with the most common mutation make a CFTR protein that is not present in the membrane.

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TLS Online TPP Program

#Question id: 28395

#Unit 5. Developmental Biology

One of the genes activated by VegT protein encodes the Sox17 transcription factor , these sox17 transcription factor is critical for which functions?
TLS Online TPP Program

#Question id: 28396

#Unit 5. Developmental Biology

VegT is critical in generating the germ cells, two genes activated by VegT protein that encodes the transcriptional factor as well as paracrine factors that instruct the cell layers to become their fate. which of the following statements is incorrect?
a) Sox17 paracrine factor that specify cells to be endoderm
b) Nodal transcription factors that instruct the cell layers above them to become mesoderm
c) Nodal paracrine factors that instruct the cell layers above them to become mesoderm
d) Sox17 transcription factor that specify cells to be endoderm
TLS Online TPP Program

#Question id: 28397

#Unit 5. Developmental Biology

During the specification of amphibian axes, in the absence of any induction cell leads to become which of the following fate?
TLS Online TPP Program

#Question id: 28398

#Unit 5. Developmental Biology

Spemann referred to the dorsal lip cells and their derivatives as the organizer, these derivatives cells are___
TLS Online TPP Program

#Question id: 28399

#Unit 5. Developmental Biology

Dorsal most vegetal cells of the blastula, which are capable of inducing the organizer is known as____
TLS Online TPP Program

#Question id: 28400

#Unit 5. Developmental Biology

Which of the following is the major candidate for the factor that forms the Nieuwkoop center ?