TLS Online TPP Program

#Question id: 2250


Which of the following is true about cystic fibrosis?

#Unit 2. Cellular Organization
  1. The normal CFTR channel protein is a chloride uniporter, but CF patients have a mutation that makes it require ATP.

  2.  CFTR mutations result in a mutated protein, which pumps too many chloride ions out of the cell.

  3. There are no treatments for patients with CF that are specifically targeted to the CFTR receptor.

  4. Patients with the most common mutation make a CFTR protein that is not present in the membrane.

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TLS Online TPP Program

#Question id: 460

#Unit 1. Molecules and their Interaction Relevant to Biology

The hydrolysis of ATP to ADP has a △G°ʹ of -30 kJ/mol. If in an E. coli cell the concentrations of ATP, ADP and inorganic phosphate are 7.90 mM, 1.04 mM and 7.9 mM, respectively, which statement is true about the hydrolysis of ATP in the cell? (Assume a temperature of 298 K. R = 8.315 J/K-mol)

TLS Online TPP Program

#Question id: 461

#Unit 1. Molecules and their Interaction Relevant to Biology

The conversion of glucose-1-phosphate to glucose-6-phosphate by the enzyme phosphoglucomutase has a △G°ʹ of -7.6 kJ/mol. Calculate the equilibrium constant for this reaction at 298 K and a pH of 7. (R = 8.315 J/K-mol)

TLS Online TPP Program

#Question id: 462

#Unit 1. Molecules and their Interaction Relevant to Biology

The formation of acetyl CoA is driven to completion by

TLS Online TPP Program

#Question id: 463

#Unit 1. Molecules and their Interaction Relevant to Biology

Thioesters are similar to oxygen esters of carboxylic acids except that

TLS Online TPP Program

#Question id: 464

#Unit 1. Molecules and their Interaction Relevant to Biology

Calculate the equilibrium constant for an oxidation-reduction reaction involving the transfer of 1 mole of electrons with DE0ʹ= 0.25 V. (R = 8.315 JK-1mol-1, F = 96.48 kJV-1mol-1, T = 298 K)

TLS Online TPP Program

#Question id: 465

#Unit 1. Molecules and their Interaction Relevant to Biology

If the standard reduction potential of a certain half-reaction is -0.30 V, which statement below is true for this half-reaction to proceed as a reduction?