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TLS Online TPP Program

#Question id: 2250

Which of the following is true about cystic fibrosis?

#Unit 2. Cellular Organization

  1. The normal CFTR channel protein is a chloride uniporter, but CF patients have a mutation that makes it require ATP.

  2.  CFTR mutations result in a mutated protein, which pumps too many chloride ions out of the cell.

  3. There are no treatments for patients with CF that are specifically targeted to the CFTR receptor.

  4. Patients with the most common mutation make a CFTR protein that is not present in the membrane.

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TLS Online TPP Program

#Question id: 19709

#Unit 3. Fundamental Processes

Following are statements related to the telomere related to the stability chromosome
a) protecting the ends of chromosomes from degradation 
b) preventing chromosomal end fusion
c) protect genome from nucleolytic degradation
d) provide a mechanism for their replication by semiconservative length maintenance 
choose the correct statement 
TLS Online TPP Program

#Question id: 19710

#Unit 3. Fundamental Processes

Telomeric sequences can be written in the general form 
TLS Online TPP Program

#Question id: 19711

#Unit 3. Fundamental Processes

Telomere are marker for the healthy cell, if the cell shows indefinite replication (embryonic or stem cell) the size of telomere lies between the range of  
TLS Online TPP Program

#Question id: 19712

#Unit 3. Fundamental Processes

Size of telomeric sequences are marker for the cell division and healthy cell,  Below some of the stages and sizes of telomere are given below

i. 3 – 20 kb (TTAGGG)n

a. cancerous cell

ii. less than 3 kb (TTAGGG)n

b. apoptotic cell death

iii. Ends with no (TTAGGG)n

c. limited replication

iv. Up to 55 kb of (TTAGGG)n

d. indefinite replication

Match them correctly
TLS Online TPP Program

#Question id: 19713

#Unit 3. Fundamental Processes

Which of the followings is the incorrect statement regarding telomeric sequences 
TLS Online TPP Program

#Question id: 19714

#Unit 3. Fundamental Processes

The extension of GGGGTT is prioritize, while the extension of CCCCAA is not possible because of