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TLS Online TPP Program

#Question id: 20284

What is the importance of C-peptide in proinsulin?

#Unit 7. System Physiology – Animal
  1. It plays an important role in the correct folding of insulin and the formation of disulfide bridge
  2. Because proinsulin and C peptide have virtually insulin activity
  3. Patients with type 1 diabetes who are unable to produce insulin will usually have greatly increased levels of C peptide.
  4. It elicits activation of at least one of these enzyme systems, sodium-potassium ATPase or endothelial nitric oxide synthase.
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TLS Online TPP Program

#Question id: 14881

#Unit 4. Cell Communication and Cell Signaling

The paradigmatic adult stem cell niche, contains several cell types that coordinate HSC development, including in column I and column II
TLS Online TPP Program

#Question id: 14882

#Unit 4. Cell Communication and Cell Signaling

In bone marrow, stem cells are committed to different lineages. Factors that stimulate colonies of these different lineages are interleukin-3 (multi-CSF), IL-7,  granulocyte- macrophage colony stimulating factor (GM-CSF) and granulocyte or macrophage colony- stimulating factor (G-CSF or M-CSF). In a mouse deficient in IL-7 the number of which cells will not be altered
TLS Online TPP Program

#Question id: 14883

#Unit 4. Cell Communication and Cell Signaling

Where is double negative selection is found during T-cell formation?
TLS Online TPP Program

#Question id: 14884

#Unit 4. Cell Communication and Cell Signaling

Which types of cell shows the middle affinity towards the self proteins? 
TLS Online TPP Program

#Question id: 14885

#Unit 4. Cell Communication and Cell Signaling

Mature T cell is found in thymus in
TLS Online TPP Program

#Question id: 14886

#Unit 4. Cell Communication and Cell Signaling

Secondary lymphoid organ provide sites where lymphocytes encounter antigen, become activated, and undergo clonal expansion and differentiation into effector cells, include
a) spleen
b) lymph node
c) mucosa-associated lymphoid tissue
Which of the following are the effector cells of secondary lymphoid organ?