TLS Online TPP Program

#Question id: 20284


What is the importance of C-peptide in proinsulin?

#Unit 7. System Physiology – Animal
  1. It plays an important role in the correct folding of insulin and the formation of disulfide bridge
  2. Because proinsulin and C peptide have virtually insulin activity
  3. Patients with type 1 diabetes who are unable to produce insulin will usually have greatly increased levels of C peptide.
  4. It elicits activation of at least one of these enzyme systems, sodium-potassium ATPase or endothelial nitric oxide synthase.