TLS Online TPP Program

#Question id: 20271


Nephrogenic diabetes insipidus is treated with thiazide diuretics. The usefulness of thiazide diuretics in treating nephrogenic diabetes insipidus is explained as follows:
a. Thiazide diuretics inhibit Na+ reabsorption in the early distal tubule. By preventing dilution of the urine at that site, the final, excreted urine is less dilute.
b. Thiazide diuretics decrease glomerular filtration rate; because less water is filtered, less water is excreted.
c. Thiazide diuretics, by increasing Na+ excretion, can cause a secondary ECF volume contraction.
Which one of the following combination of above statements is correct?

#Unit 7. System Physiology – Animal
  1. a and b
  2. b and c
  3. a and c
  4. a, b and c