Which of the following is true about interphase chromosome

a. Interphase chromosomes occupy chromosome territories in the nucleus

b. Interphase chromosomes occupy chromosome territories toward cell membrane 

c. Interphase chromosomes are not entangled with each other except cancer 

d. Interphase chromosomes are entangled with each other except cancer 

#Question id: 4694

#Unit 3. Fundamental Processes

Which nuclear bodies are centers of RNP-complex assembly for spliceosomal snRNPs and other RNPs ?

#Question id: 4695

#Unit 3. Fundamental Processes

snRNAs undergo specific post-transcriptional modifications, such as pseudouridinylylation and the addition of methyl groups. These modifications occur in__A__,  where they are directed by__B_.

#Question id: 4696

#Unit 3. Fundamental Processes

U6 snRNPs is transcribed by

#Question id: 4697

#Unit 3. Fundamental Processes

Nuclear Paraspeckles is a site for

#Question id: 4818

#Unit 3. Fundamental Processes

Researchers found a strain of E. coli bacteria that had mutation rates one hundred times higher than normal. Which of the following statements correctly describes the most likely cause of these results?

#Question id: 4950

#Unit 3. Fundamental Processes

Temperature-sensitive (ts) mutations, which are one form of conditional lethal mutation, allow cells to grow at one temperature (for example, 30°C) but not at a higher temperature (for example, 42°C). A large number of temperature-sensitive replication mutants have been isolated in E. coli. These mutant bacteria are defective in DNA replication at 42°C but not at 30°C. If the temperature of the medium is raised from 30°C to 42°C, these mutants stop making DNA in one of two characteristic ways. The “quick-stop” mutants halt DNA synthesis immediately, whereas the “slow-stop” mutants stop DNA synthesis only after many minutes. Extracts from quick-stop mutants halt DNA synthesis immediately at 42°C, whereas extracts from slow-stop mutants do not stop DNA synthesis for several minutes after a shift to 42°C. Suppose extracts from a temperature-sensitive DNA helicase mutant and a temperature-sensitive DNA ligase mutant were mixed together at 42°C. Which of the following statements are correct?

A. The mixed extracts should be fully competent for DNA replication at 30°C; that is, the mixture should exhibit a nonmutant phenotype.

B. The defective DNA helicase extract would provide normal DNA ligase, and the defective DNA ligase extract would provide normal DNA helicase.

C. In practice, the behaviors of extracts from slow-stop mutants and from nonmutant cells are easy to distinguish.

D. Because of the extreme complexity of DNA replication and the large number of proteins involved, cell-free extracts are not capable of maintaining DNA replication indefinitely.