#Question id: 3855
#Unit 3. Fundamental Processes
In eukaryotes, which of the following modifications is made to a primary transcript prior to its transport out of the nucleus?
#Question id: 15657
#Unit 13. Methods in Biology
#Question id: 1431
#Unit 4. Cell Communication and Cell Signaling
Which of the following is NOT a role for the tumor microenvironment?
#Question id: 1521
#Unit 4. Cell Communication and Cell Signaling
we examine how the deregulation of growth-promoting and growth-inhibiting signaling pathways contributes to tumorigenesis. Mutations-
A. A mutation that alters a single amino acid (valine to glutamine) in the transmembrane region of the HER2 receptor
B. A deletion that causes loss of the extracellular ligand-binding domain in the EGF receptor Results-
i. dimerization of the receptor, even in the absence of the normal EGF-related ligand, transforming it into the oncoprotein, a constitutively active kinase
ii. to constitutive activation of the kinase activity of the resulting oncoprotein
iii. no dimerization, even in the presence of the normal EGF-related ligand, repression of kinase activity
which of the following results are displayed after these mutations?
#Question id: 2593
#Unit 2. Cellular Organization
How do actin filaments appear when viewed by negative stain electron microscopy?