TLS Online TPP Program

#Question id: 266


________ plays an important role in storing the energy needed for the unwinding of DNA during replication, recombination, repair and transcription.

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. A high percent of G:C base pairs

  2. The charge on basic side chains of histone proteins

  3. Negative supercoiling

  4. Overwinding of the helix

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TLS Online TPP Program

#Question id: 173

#Unit 1. Molecules and their Interaction Relevant to Biology

What is the net charge on the tripeptide Gly-Arg-Lys at pH 7? The table below gives the pKaʹs of the ionizable groups on the free amino acids.

TLS Online TPP Program

#Question id: 174

#Unit 1. Molecules and their Interaction Relevant to Biology

What is the net charge on the dipeptide Arg-Pro at pH 9.0? The table below gives the pKaʹs of the ionizable groups on the free amino acids.

TLS Online TPP Program

#Question id: 175

#Unit 1. Molecules and their Interaction Relevant to Biology

The ionic charges associated with a protein molecule are ________.

TLS Online TPP Program

#Question id: 176

#Unit 1. Molecules and their Interaction Relevant to Biology

A peptide has the sequence Glu–His–Trp–Ser–Gly–Leu–Arg–Pro–Gly. What is the net charge of the molecule at pH 3

TLS Online TPP Program

#Question id: 177

#Unit 1. Molecules and their Interaction Relevant to Biology

The titration curve of alanine shows the ionization of two functional groups with pKa values of 2.34 and 9.69, corresponding to the ionization of the carboxyl and the protonated amino groups, respectively. The titration of di-, tri-, and larger oligopeptides of alanine also shows the ionization of only two functional groups, although the experimental pKa values are different. The trend in pKa values is summarized in the table. Which of the following is a reason for this shift in pK values

TLS Online TPP Program

#Question id: 178

#Unit 1. Molecules and their Interaction Relevant to Biology

Given the pKa values of different acidic sites in cysteine, the principal ionic form which will never exist at any pH