TLS Online TPP Program

#Question id: 2533


Cellulose microfibrils have an ordered structure and are synthesized at the plasma membrane, given characteristics of microfibrils;

a) Each microfibril is composed of an estimated 18 parallel chains of (1,4)-linked β-D-glucose chains tightly bonded to each other to form a crystalline microfibril

b) Microfibrils have hydrophilic surfaces, populated by polar –OH groups extending from theplane of the sugar rings

c) Microfibrils have hydrophobic surfaces, populated by nonpolar C–H groups populating thesides of stacked glucose chains

 d) microfibril important for enzymatic attack by microbial cellulases, which dock onto the hydrophobic surface and remove one glucan chain at a time

Which of the following from given characterstics of microfibrils is incorrect?

#Unit 2. Cellular Organization
  1. Only B    

  2. A and C   

  3. B and C           

  4. Only D

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TLS Online TPP Program

#Question id: 846

#Unit 1. Molecules and their Interaction Relevant to Biology

The maintenance of the steady-state collection of active cellular proteins required under a particular set of conditions, called ______.

TLS Online TPP Program

#Question id: 847

#Unit 1. Molecules and their Interaction Relevant to Biology

A proposed pathway for the action of E.coli chaperonins  are groEL and groES.groEL exist in trans and cis structure transferring with its bound ATP now become the cis ring once the groES  bound to it ATP hydrolysis takes place and improperly folded protein get properly folded, total number of  ATP molecules are required to per folding cycle;

TLS Online TPP Program

#Question id: 848

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the brain diseases is not caused by the misfolding of brain proteins in mammals

TLS Online TPP Program

#Question id: 849

#Unit 1. Molecules and their Interaction Relevant to Biology

The rigidity of the peptide unit and the restricted set of allowed phi and psi angles limits the number of structures accessible to the unfolded form sufficiently to allow:-

TLS Online TPP Program

#Question id: 850

#Unit 1. Molecules and their Interaction Relevant to Biology

The experimental inverse of protein structure prediction, has provided insights into protein folding and stability. Protein design attempts to construct an amino acid sequence that will form a structure such as a sandwich of β sheets or a bundle of α helices;

TLS Online TPP Program

#Question id: 851

#Unit 1. Molecules and their Interaction Relevant to Biology

Methods is the Rosetta program, formulated by David Baker. To satisfy the program’s computational needs, a volunteer network of ∼100,000 computers, known as Rosetta@home, provides the 500,000 or so hours of processing time required to generate a structure;