TLS Online TPP Program

#Question id: 23101


Choose the incorrect statement 

#Unit 2. Cellular Organization
  1. The nucleosome is 200 bp of DNA, organized by an octamer of small, basic histone proteins into a beadlike structure. 
  2. The nucleosome is of 20nm/200A diameter, compacting the DNA about 13-fold over the length of naked DNA. Its first level of organization
  3. The second level of organization is the coiling of the 10-nm fiber of nucleosomes into a helical array to constitute the fiber of diameter 30 nm.
  4. 30 nm compacts the DNA 40-fold. This structure of this fiber requires the histone tails and is stabilized by linker histones
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TLS Online TPP Program

#Question id: 4465

#Unit 3. Fundamental Processes

Main function of Nus proteins in transcription,

TLS Online TPP Program

#Question id: 4466

#Unit 3. Fundamental Processes

As well as synthesizing the transcript, RNA polymerase performs two proofreading functions on that growing transcript;

i. Pyrophosphorolytic editing

ii. Hydrolytic editing

Choose correct processes accordingly,

A. The polymerase backtracks by one or more nucleotides and cleaves the RNA product, removing the error-containing sequence.

B. In this, the enzyme uses its active site, in a simple back-reaction,

C. Catalyze the removal of an incorrectly inserted ribonucleotide, by reincorporation of PPi

D. The enzyme can then incorporate another ribonucleotide in its place in the growing RNA chain.

TLS Online TPP Program

#Question id: 4467

#Unit 3. Fundamental Processes

Both polymerase removal and repair enzyme recruitment are performed by a single protein called?

TLS Online TPP Program

#Question id: 4468

#Unit 3. Fundamental Processes

Major role of TRCF 

TLS Online TPP Program

#Question id: 4469

#Unit 3. Fundamental Processes

Termination is a normal and important function at the ends of genes. There, sequences called terminators trigger the elongating polymerase to dissociate from the DNA and release the RNA chain it has made, In bacteria, terminators come in two types: Rho-dependent and Rho-independent, choose correct statements about this;

Rho-dependent

a- rut sites

b- has an ATPase activity

Rho-independent

c- terminates only those transcripts still being transcribed beyond the end of a gene or operon

d- intrinsic terminator

TLS Online TPP Program

#Question id: 4470

#Unit 3. Fundamental Processes

Most recent experiments suggest that the last of these is at least an important part of the story and that the conformational change causes the elongating complex to stall, with dissociation following more slowly- this conformational change caused by,