Which of the following statement is true regarding second level of organization 

a. The second level of organization is the coiling of the 10-nm fiber of nucleosomes into a helical array.

b. The coiled helical array to constitute the fiber of diameter 30 nm that is found in interphase chromatin and in mitotic chromosomes.

c. This compacts the DNA - 40-fold. The structure of this fiber requires the histone tails and is stabilized by linker histones.

d. Histone H1, histone tails, and increased ionic strength all promote the formation of the 30-nm fiber.

#Question id: 29440

#Unit 1. Molecules and their Interaction Relevant to Biology

#Question id: 4423

#Unit 1. Molecules and their Interaction Relevant to Biology

Each repeat unit within the nuclear ribosomal gene cluster of eukaryotes (rDNA) contains

#Question id: 10308

#Unit 1. Molecules and their Interaction Relevant to Biology

Oxidative decarboxylation of pyruvate to acetyl-CoA by the PDH complex, how the pyruvate dehydrogenase complex carries out the five consecutive reactions in the decarboxylation and dehydrogenation of pyruvate?

 A) Pyruvate reacts with the bound thiamine pyrophosphate (TPP) of pyruvate dehydrogenase, undergoing decarboxylation to the hydroxyethyl derivative

 B) A transesterification in which the —SH group of CoA replaces the —SH group of E2 to yield acetyl-CoA and the fully reduced (dithiol) form of the lipoyl group

 C) The reduced FADH2 of E3 transfers a hydride ion to NAD1 , forming NADH, the enzyme complex is now ready for another catalytic cycle

 D) The transfer of two electrons and the acetyl group from TPP to the oxidized form of the lipoyllysyl group of the core enzyme, dihydrolipoyl transacetylase, to form the acetyl thioester of the reduced lipoyl group

 E) Dihydrolipoyl dehydrogenase promotes transfer of two hydrogen atoms from the reduced lipoyl groups of E2 to the FAD prosthetic group of E3 , restoring the oxidized form of the lipoyllysyl group of E2

 Find out the correct sequence of action of this complex enzyme?

#Question id: 30093

#Unit 1. Molecules and their Interaction Relevant to Biology

Which compound forms IMP through Hypoxanthine guanine phosphoribosyltransferase enzyme?

#Question id: 30094

#Unit 1. Molecules and their Interaction Relevant to Biology

Name the genetic disorder which is caused by the deficiency of enzyme HGPRT?

#Question id: 30095

#Unit 1. Molecules and their Interaction Relevant to Biology

In tissues that do not carry out active de novo synthesis, maintenance of an adequate supply of adenine nucleotides: