TLS Online TPP Program

#Question id: 23111


Choose the correct option 
a. Individual nucleosomes can be obtained by treating chromatin with the endonuclease micrococcal nuclease (MNase), which cuts the DNA between nucleosomes, a region known as H2A-H2B dimer region. 
b. Individual nucleosomes can be obtained by treating chromatin with the endonuclease micrococcal nuclease (MNase), which cuts the DNA between nucleosomes, a region known as linker DNA.
c. Mononucleosomes typically have 200 bp DNA. End-trimming reduces the length of DNA first to 165 bp and then generates core particles with 146 bp.
d. Mononucleosomes typically have 200 bp DNA. End-trimming reduces the length of DNA first to 165 bp and then generates core particles with 200 bp.

#Unit 2. Cellular Organization
  1. a only
  2. a and b 
  3. b, and c 
  4. a, b, c, and d
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TLS Online TPP Program

#Question id: 28693

#Unit 2. Cellular Organization

There are some given statements about co-translational translocation in endoplasmic reticulum

a)SRP and the nascent polypeptide chain–ribosome complex bind to the integral membrane translocon

b)SRP and the nascent polypeptide chain–ribosome complex is strengthened by the binding of GTP to both the SRP and its receptor.

c)ER signal sequence emerges from the ribosome, it is bound by a signal recognition particle (SRP)

d)Hydrolysis of the bound GTP accompanies disassembly of the SRP and SRP receptor

e)Hydrolysis of the bound GTP initiates opening of the translocon, where translocation can take place


Which of the following statement is incorrect?

TLS Online TPP Program

#Question id: 28694

#Unit 2. Cellular Organization

Which one of the following was first identified through mutations in the yeast gene and encoding a protein called Sec61α?

TLS Online TPP Program

#Question id: 28695

#Unit 2. Cellular Organization

O-linked oligosaccharides is representing the attachment of glycoproteins to the hydroxyl (–OH) group in which amino acid residue?

TLS Online TPP Program

#Question id: 28696

#Unit 2. Cellular Organization

N-linked oligosaccharide is attaching carbohydrate chain to the amide nitrogen of which amino acid residue?

TLS Online TPP Program

#Question id: 28697

#Unit 2. Cellular Organization

Biosynthesis of all N-linked oligosaccharides begins in the rough ER with a preformed branched oligosaccharide precursor containing_____
i) Glucose (Glc)
ii) Galactose
iii) Mannose (Man)
iv) N-acetylglucosamine (GlcNAc)
v) N-acetylgalactosamine (GalNAc)

TLS Online TPP Program

#Question id: 28698

#Unit 2. Cellular Organization

the oligosaccharide precursor is assembled on a membrane- attached anchor called dolichol phosphate, which is___