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#Unit 5. Developmental Biology
Few statements regarding the role of disheveled (dsh) and beta-catenin in the
development of sea urchin.
A.
beta-catenin accumulates predominantly in the macromeres and somewhat in veg2
tier cells.
B.
At the fourth cleavage disheveled and β-catenin, both of which are found in the
cytoplasm and are inherited by the micromeres.
C.
Treating sea urchin embryos with lithium chloride allows β-catenin to
accumulate in every cell and transforms presumptive ectoderm into endoderm.
D.
When β-catenin is prevented from entering the nuclei (i.e., it remains in the
cytoplasm), the vegetal cell fates are specified, and the entire embryo
develops as a ciliated ectodermal ball.
Which one of the following options represents a combination of correct statement?