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TLS Online TPP Program

#Question id: 2576

What effect will addition of AMP-PNP have on axonal transport?

#Unit 2. Cellular Organization

  1. AMP-PNP induces tight binding of myosin (and most other microtubule motors) to microtubules; therefore, vesicle transport would cease because the motors would be locked onto the microtubules.

  2.  AMP-PNP induces tight binding of dynein (and most other microtubule motors) to microtubules; therefore, vesicle transport would cease because the motors would be locked onto the microtubules.

  3. AMP-PNP induces tight binding of kinesin (and most other microtubule motors) to microtubules; therefore, vesicle transport would cease because the motors would be locked onto the microtubules.

  4. AMP-PNP induces tight binding of myosin and kinesin (and most other microtubule motors) to microtubules; therefore, vesicle transport would cease because the motors would be locked onto the microtubules.

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TLS Online TPP Program

#Question id: 1196

#Unit 4. Cell Communication and Cell Signaling

Cell signaling means all of the following except:
TLS Online TPP Program

#Question id: 1197

#Unit 4. Cell Communication and Cell Signaling

In a signal transduction pathway, what is passed from the upstream member of the pathway to the downstream member?
TLS Online TPP Program

#Question id: 1198

#Unit 4. Cell Communication and Cell Signaling

Both epinephrine and glucagon bind to G protein-coupled receptors and activate glycogen breakdown. Therefore, epinephrine and glucagon must:
TLS Online TPP Program

#Question id: 1199

#Unit 4. Cell Communication and Cell Signaling

If you break liver cells by homogenization, separate the broken cell membranes (particulate) from the cytoplasm (soluble), and add epinephrine to the soluble portion, the result will be:
TLS Online TPP Program

#Question id: 1200

#Unit 4. Cell Communication and Cell Signaling

Glucagon binds to the glucagon receptor, which interacts with a membrane-bound G protein, whose α subunit releases GDP and binds GTP. The α subunit then dissociates from the G protein and diffuses to a membrane-bound adenylyl cyclase which produces cAMP. In this scenario, name the

(1) transducer,

(2) effector,

(3) first messenger, and

(4) second messenger.
TLS Online TPP Program

#Question id: 1201

#Unit 4. Cell Communication and Cell Signaling

Epinephrine binds to the same type of receptors in liver, fat, and smooth muscle cells. Yet in liver, glycogen breaks down; in fat, triacylglycerols break down; and smooth muscle cells relax. How can the same hormone produce three such different responses?