TLS Online TPP Program

#Question id: 2582


Following statements are regarding to dynamics of actin filaments.

A. When the concentration of G-actin is above the Cc, the filament end will grow; when it is less than the Cc, the filament will shrink.

B. ATP–G-actin is added much faster at the (+) end than at the (−) end, resulting in a lower critical concentration at the (+) end than at the (−) end.

C. At steady state, actin subunits treadmill through a filament. ATP-actin is added at the (+) end, ATP is then hydrolyzed to ADP and Pi, Pi is lost, and ADP-actin dissociates from the (−) end.

D. ATP–G-actin is added much faster at the (-) end than at the (+) end, resulting in a lower critical concentration at the (-) end than at the (+) end.

E. At steady state, actin subunits treadmill through a filament. ATP-actin is added at the (-) end, ATP is then hydrolyzed to ADP and Pi, Pi is lost, and ADP-actin dissociates from the (+) end.

Which of the following statements are correct?

#Unit 2. Cellular Organization
  1. A, B and C

  2. B, D and E

  3. A, C and E

  4. A and D only