Practice Questions

TLS Online TPP Program

#Question id: 2588

Which of the following statement is correct regarding attachment of microtubule to the kinetochore?

#Unit 2. Cellular Organization

Once a kinetochore is attached laterally or terminally to a microtubule, dynein-dynactin associates with the kinetochore to move the duplicated chromosome down the microtubule toward the spindle pole. This movement eventually results in an end-on attachment of the microtubule to one kinetochore.
Once a kinetochore is attached laterally or terminally to a microtubule, kinesin associates with the kinetochore to move the duplicated chromosome down the microtubule toward the spindle pole. This movement eventually results in an end-on attachment of the microtubule to one kinetochore.
Once a kinetochore is attached laterally or terminally to a microtubule, myosin associates with the kinetochore to move the duplicated chromosome down the microtubule toward the spindle pole. This movement eventually results in an end-on attachment of the microtubule to one kinetochore.
Kinesin-13 provides the strongest force pulling the chromosome pair toward the more distant pole. This movement requires simultaneous shortening of the microtubule, which is enhanced by kinetochore-localized dynein-dynactin.