TLS Online TPP Program

#Question id: 2737


The linking number (Lk) of a closed-circular, double-stranded DNA molecule is changed by:

#Unit 2. Cellular Organization
  1. breaking a strand, unwinding or rewinding the DNA, then rejoining it.

  2. breaking all hydrogen bonds in the DNA.

  3. supercoiling without the breaking of any phosphodiester bonds.

  4. underwinding without the breaking of any phosphodiester bonds.

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TLS Online TPP Program

#Question id: 1396

#Unit 4. Cell Communication and Cell Signaling

Trks are:

a. endonucleases.        b. transmembrane receptors.   c. proteases.     d. protein kinases.      

TLS Online TPP Program

#Question id: 1397

#Unit 4. Cell Communication and Cell Signaling

The vertebrate equivalent of CED-9 is:

TLS Online TPP Program

#Question id: 1398

#Unit 4. Cell Communication and Cell Signaling

Which of the following properties is (are) characteristic of a benign tumor?

a. well differentiated              b. localized to tissue of origin             c. metastatic               

d. promotes angiogenesis        e. surrounded by a fibrous capsule

TLS Online TPP Program

#Question id: 1399

#Unit 4. Cell Communication and Cell Signaling

Loss-of-function mutations in which of the following genes typifies colorectal carcinomas?

a. myc              b. K-ras                       c. p53              d. APC

TLS Online TPP Program

#Question id: 1400

#Unit 4. Cell Communication and Cell Signaling

Which property is shared by malignant tumor cells and transformed cells in culture?

a. reduced growth factor requirement                        b. attachment-dependent growth

c. loss of actin microfilaments                                    d. altered morphology

TLS Online TPP Program

#Question id: 1401

#Unit 4. Cell Communication and Cell Signaling

Which of the following are proto-oncogenes?

a. fos               b. myc             c. p53              d. ras               e. Rb