Match the lac genes with their enzymes & functions;

lac genes	Enzyme	Functions
lacZ	b-galactosidase	which rids the cell of toxic thiogalactosides that also get transported in by lacY.
lacY	thiogalactoside transacetylase	which cleaves the sugar lactose into galactose and glucose, both of which are used by the cell as energy sources
lacA	lactose permease	a protein that inserts into the cell membrane and transports lactose into the cell

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#Question id: 12503

#Unit 8. Inheritance Biology

In this pedigree II 1 is affected with an autosomal recessive disorder. The disease status for II 2 is unknown. A and B represent alleles at a locus which is tightly linked to the disease locus with recombination fraction of 0. Using the linked markers, II2 can be told that:

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#Question id: 12504

#Unit 8. Inheritance Biology

In this pedigree II 3 and III 1 are affected with an X-linked recessive disorder which is tightly linked to a marker locus with alleles A and B, with a recombination fraction of 0 between the disease and marker loci. Analysis of the linked marker results indicates that the disease must be segregating with:

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#Question id: 12505

#Unit 8. Inheritance Biology

The marker genotype for I 2 must have been:

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#Question id: 12506

#Unit 8. Inheritance Biology

Using the linked markers III 3 can be told that:

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#Question id: 12507

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that III 3 is a carrier of Becker muscular dystrophy?

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#Question id: 12508

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.

What is the probability that III 3 is a carrier of oculocutaneous albinism?