From the following set of statements regarding DNA topology, state whether each of the given statement is either True or False.

A.      The two strands of cccDNA can be easily separated without any breakage of bonds.

B.      Circular DNA molecules purified from bacteria and eukaryotes are usually negatively supercoiled.

C.      Interwound writhe and spiral writhe are topologically different.

D.      The organisms that live under extreme temperature conditions have been found to have positively supercoiled DNA.

E.      Negative supercoils can be thought of as a store of free energy that aids in processes that require strand separation.

#Question id: 5722

#Unit 8. Inheritance Biology

Meiotic products resulting from a single crossover within a pericentric inversion loop

A. This will generate a dicentric and an acentric chromosome following separation of chromosomes after crossing over

B. the inversion will completely suppress crossing over

C. All parental gametes that carry inversion chromosome are nonviable

D. All gametes from crossover products are non viable due to appearance of duplication of one arm and deletion of another arm

Which of the above statements are correct?

#Question id: 5723

#Unit 8. Inheritance Biology

An individual heterozygous for a reciprocal translocation possesses the following chromosomes

I-  nonviability                                  II – Viability        

III- only translocated chromosome     IV- only normal chromosome

V- one translocated another normal

Which of the following above chromosome constituent and feature in their gamete result from?

A- alternate       B- adjacent-1     C- adjacent-2

#Question id: 5724

#Unit 8. Inheritance Biology

Species I is diploid (2n  = 8) with chromosomes

AABBCCDD; related species II is diploid (2n = 8) with chromosomes MMNNOOPP. Individuals with the following sets of chromosomes represent what types of chromosome mutations?

A-   AAABBCCDD        B-   AABBCCDDMNOP

C-   AAABBCCDDD

#Question id: 5725

#Unit 8. Inheritance Biology

An individual is having an inversion in heterozygous condition. The regions on normal chromosome are marked as A, B, C, D, E, F, G while the chromosome having inversion has the regions as a, b, e, d, c, f, g. The diagram given below shows pairing of these two homologous chromosomes during meiosis and the site of a crossing over is indicated:

The following statements are given to describe the inversion and the consequence of crossing over shown in the above diagram:

A. This is a paracentric inversion

B. This will generate a dicentric and an acentric chromosome following separation of chromosomes after crossing over

C. This will generate two recombinant chromosomes with deletion and other parental chrmosome following separation of chromosomes after crossing over

D. 50 % gametes will be non viable due to deletion or duplication of chromatids

E. The gametes having recombinant chromatid or parental inversion chromatids will be non-viable

#Question id: 5726

#Unit 8. Inheritance Biology

Following diagram represents the sequence of genes in a normal chromosome of a plant species

CORRECT combination for chromosomal mutation using

#Question id: 5727

#Unit 8. Inheritance Biology

Pairing occurs during the prophase of meiosis I, after the chromosomes have been duplicated. Centromere mention as 1, 2, 3 and 4

Which of the following is correct statement Types of disjunction in a translocation heterozygote during meiosis I.

A) Centromeres 1 and 3 go to one pole and centromeres 2 and 4 go to the other pole, producing non fuctional gametes.

B) Centromeres 1 and 2 go to one pole and centromeres 3 and 4 go to the other pole, producing viable gametes.

C) Centromeres 2 and 3 go to one pole and centromeres 1 and 4 go to the other pole, producing euploid gametes.

D) Centromeres 2 and 3 go to one pole and centromeres 1 and 4 go to the other pole, producing non viable gamete