TLS Online TPP Program

#Question id: 2882


SUMO (small ubiquitin-related modifier) proteins are ∼10-kD polypeptides that function as reversible post-translational protein modifiers. They form isopeptide bonds with ɛ-amino groups of acceptor Lys residues in hundreds of target proteins in a process termed as sumoylation. Which of the following statements is correct regarding this modification?

#Unit 2. Cellular Organization
  1. A short non-covalent SUMO-interaction/binding motif (SIM/SBM) has been identified in all SUMO enzymes, targets and downstream effectors. This motif contributes to the mechanism and consequences of sumoylation.

  2. Acceptor Lys residues in target proteins are frequently found in the consensus motif ΨKxD although the number of targets with non-consensus acceptor sites is steadily increasing.

  3. Irreversible sumoylation contributes to many distinct pathways, such as chromatin structure, DNA repair, transcription, cell-cycle progression and trafficking.

  4. Sumoylation alters the molecular interactions of modified target proteins by masking or adding interaction surfaces. Downstream consequences, which are target dependent, include changes in localization, activity and protein stability.

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TLS Online TPP Program

#Question id: 26587

#Unit 3. Fundamental Processes

Circularisation of telomere known as

TLS Online TPP Program

#Question id: 26588

#Unit 3. Fundamental Processes

Which of the following statement is incorrect regarding Cdc 13

TLS Online TPP Program

#Question id: 26589

#Unit 3. Fundamental Processes

Which proteins regulates number of repeats in RNA component for telomere lengths

TLS Online TPP Program

#Question id: 26787

#Unit 8. Inheritance Biology

In the S phase of meiotic interphase, each chromosome replicates, producing two copies of each allele, one on each chromatid, the homologous chromosomes segregation takes place in__

Which of the following statements is correct about the segregation of chromosomes?

a.If no crossing over has taken place, the two chromatids of each chromosome segregate in anaphase II and are identical

b. If crossing over has taken place, the two chromatids are no longer identical, and the different alleles segregate in anaphase II

c. If no crossing over has taken place, the two chromatids of each chromosome segregate in anaphase I and are identical

TLS Online TPP Program

#Question id: 26788

#Unit 8. Inheritance Biology

Which of the following factors did not contribute to Mendel’s success in his study of heredity?

a.His use of the monoecious pea plant

b.His study of plant chromosome

c.His adoption of an experimental approach

d.His use of mathematics

e.The Plant use is easy to cultivate

TLS Online TPP Program

#Question id: 26789

#Unit 8. Inheritance Biology

Given below are types of crossing in column II and their associated features/effects/functions in column I

 Select the correct set of combinations from the options given below: