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#Question id: 2883


Which, if any, of the following statements is incorrect?

I. In X-chromosome inactivation, the inactivated X chromosome is epigenetically silenced by a transcript, the XIST RNA, that is produced from the active X chromosome.

II. The XIST RNA works by coating most of the X chromosome that is to be inactivated and then recruiting Polycomb proteins to condense the chromosome.

III. The inactivated X chromosome carries the kinds of histone modification that are typical of heterochromatin.

IV. The pattern of X-chromosome inactivation is made randomly but once it has been established the same pattern of X-inactivation is propagated through all mitotic and meiotic cell divisions.

#Unit 2. Cellular Organization
  1. I and III only

  2. I and IV only

  3. I, II and III only

  4. II and IV only

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TLS Online TPP Program

#Question id: 10931

#Unit 7. System Physiology – Animal

A 24-year-old African-American man comes to the emergency room 3 hr after the onset of severe back and chest pain. These problems started while he was skiing. He lives in Los Angeles and had a previous episode of these symptoms 5 years ago while visiting Wyoming. He is in obvious pain. Laboratory studies show the following:

Hemoglobin                                        11 gm/dl

Leukocyte count                                 22,000/μl3

Reticulocyte count                              25%

What is the diagnosis of this patient?

TLS Online TPP Program

#Question id: 10932

#Unit 7. System Physiology – Animal

A 62-year-old man complains of headaches, visual difficulties, and chest pains. His examination shows a red complexion and a large spleen. His complete blood count follows: hematocrit, 58%, WBC 13,300/μl, and platelets 600,000/μl. His arterial oxygen saturation is 97% on room air. Which of the following would you recommend as a treatment?

TLS Online TPP Program

#Question id: 10933

#Unit 1. Molecules and their Interaction Relevant to Biology

Imidazole ring is the characteristic of which amino acid


TLS Online TPP Program

#Question id: 10934

#Unit 1. Molecules and their Interaction Relevant to Biology

Carboxy terminus is protonated at ………………while amino terminus will be deprotonated at………..

TLS Online TPP Program

#Question id: 10935

#Unit 1. Molecules and their Interaction Relevant to Biology

The pH at which imidazole of histidine ring will be protonated………….. and imine group of proline will be deprotonated…………….

TLS Online TPP Program

#Question id: 10936

#Unit 1. Molecules and their Interaction Relevant to Biology

Which type of chemical bonds are required to produce an absorption spectrum in UV-visible region? the molecule must contain