Which, if any, of the following statements is incorrect?

I. In X-chromosome inactivation, the inactivated X chromosome is epigenetically silenced by a transcript, the XIST RNA, that is produced from the active X chromosome.

II. The XIST RNA works by coating most of the X chromosome that is to be inactivated and then recruiting Polycomb proteins to condense the chromosome.

III. The inactivated X chromosome carries the kinds of histone modification that are typical of heterochromatin.

IV. The pattern of X-chromosome inactivation is made randomly but once it has been established the same pattern of X-inactivation is propagated through all mitotic and meiotic cell divisions.

TLS Online TPP Program

#Question id: 27985

#Unit 1. Molecules and their Interaction Relevant to Biology

Over all net reaction for Q cycle is

TLS Online TPP Program

#Question id: 28035

#Unit 1. Molecules and their Interaction Relevant to Biology

Intrinsically disordered proteins  

a. Have hydrophobic core

b. High densities of charged amino acid residues 

c. Pro residues are also prominent

d. Generally promiscus in nature

e. lack a hydrophobic core

Which of the following is correct 

TLS Online TPP Program

#Question id: 28036

#Unit 1. Molecules and their Interaction Relevant to Biology

The protein p27 is

a. a highly ordered protein

b. a intrinsically disordered protein

c. p27 inhibits cyclin-dependent kinases (CDKs)  

d. p27 promotes cyclin-dependent kinases (CDKs

Which of the following is correct

TLS Online TPP Program

#Question id: 28037

#Unit 1. Molecules and their Interaction Relevant to Biology

Intrinsically disordered proteins have properties that are distinct from classical structured proteins, so which of the following's statements are true regarding Intrinsically disordered proteins 

(1) Intrinsically disordered proteins  lacks hydrophobic core

(2) Intrinsically disordered proteins have a hydrophobic core

(3) Intrinsically disordered proteins have high densities of charged amino acid residues such as Lys, Arg, and Glu

(4) Functional promiscuity is the characteristics of  Intrinsically disordered proteins are.

TLS Online TPP Program

#Question id: 28038

#Unit 1. Molecules and their Interaction Relevant to Biology

PONDR (Predictor of Natural Disordered Regions) A score of 1.0 indicates a probability of 

TLS Online TPP Program

#Question id: 28039

#Unit 1. Molecules and their Interaction Relevant to Biology

Proteins particularly those with molecular masses >100 kD, consist of more than one polypeptide chain. These polypeptide subunits associate with a specific geometry. The spatial arrangement of these subunits is known as