TLS Online TPP Program

#Question id: 2887


Which of the following reasons has led to the evolutionary selection of an extra methyl group in DNA?

#Unit 2. Cellular Organization
  1. Thymine is more stable than Uracil due to the absence of an extra methyl group attached to the 5’ position.

  2. Cytosine undergoes spontaneous deamination to yield Uracil, which repair enzymes cannot recognize as foreign to DNA.

  3. If the genetic material contained uracil, then uracil arising from cytosine deamination would go undetected by the surveillance systems that maintain the genome.

  4. Uracil has greater resistance to photochemical mutation, making the genetic material more stable.

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TLS Online TPP Program

#Question id: 5286

#Unit 8. Inheritance Biology

An Hfr strain with genotype A B C D (each gene for amino acid synthesis )and that transfers the A gene very late was mated with recipient strain with genotype a b c d. After mating for several hours, the mixture was diluted and plated on minimal media with four different supplements having various number of colony

Media supplement with amino acid  

                 Colony                                          number

                  A+C                                                 500

                  C+D                                                  50

                     B                                                    10

                     A                                                   250

What is order of gene

TLS Online TPP Program

#Question id: 5287

#Unit 8. Inheritance Biology

Interrupted matting of different Hfr strain with F- E.coli cell resulting generation of following strain  Order of gene is

TLS Online TPP Program

#Question id: 5288

#Unit 8. Inheritance Biology

Donor strain of bacteria with His+ Ara+ Met+ Leu+ Cys+ Lys+ is infected with phages to map the donor chromosome with generalized transduction .The Phage lysate from bacterial cell is collected and use to infect second strain of bacteria that are His- Ara- Met- Leu- Cys- Lys- . Different transducing phages are selected on using different minimal media and their presence of growth (+) and absence of growth (-) given in table

Media

Media supplement 0 absent /+ present

1

His

Ara

Met

Leu

Cys

Lys

Growth

2

+

+

0

+

+

0

+

3

0

+

+

+

+

0

+

4

+

+

0

+

0

+

-

5

0

+

+

0

+

+

+

6

+

0

+

0

+

+

+

7

+

0

+

+

0

+

+

Which of the following is correct order of gene?

TLS Online TPP Program

#Question id: 5289

#Unit 8. Inheritance Biology

A donor strain of bacteria with genes a+b+c+ is infected with phages to map the donor chromosome with transduction. The phage lysate from the bacterial cells is collected and used to infect a second strain of bacteria that are a_ b_ c_.

Based on the above, which one of the following conclusions is correct?

TLS Online TPP Program

#Question id: 5290

#Unit 8. Inheritance Biology

The following table shows mapping data from three interrupted mating experiments using three different Hfr strains and an F- strain: The order of genes is

TLS Online TPP Program

#Question id: 5291

#Unit 8. Inheritance Biology

A number of nutritional mutant strains were isolated from wild-type Neurospora that responded to the addition of certain supplements in the culture medium by growth ( + ) or lack of growth ( -). Given the following responses for single gene mutations, diagram a metabolic pathway that could exist in the wild-type strain that is most consistent with the data. Indicate where the pathway is blocked in each mutant strain.