TLS Online TPP Program

#Question id: 2889


The edges of each base pair are exposed in the major and minor grooves, creating a pattern of hydrogen-bond donors and acceptors and of hydrophobic groups (allowing for Vander Waals interactions) that identifies the base pair. The edge of an C : G base pair displays the following chemical groups in the following order in the major groove:

#Unit 2. Cellular Organization
  1. A hydrogen-bond acceptor (at N7 of guanine), a hydrogen-bond acceptor (the carbonyl on C6 of guanine), a hydrogen-bond donor (the exocyclic amino group on C3 of cytosine), and a small nonpolar hydrogen (the hydrogen at C5 of cytosine)

  2. A hydrogen-bond acceptor (at N7 of guanine), a hydrogen-bond acceptor (the carbonyl on C6 of guanine), a hydrogen-bond donor (the exocyclic amino group on C4 of cytosine), and a small nonpolar hydrogen (the hydrogen at C5 of cytosine)

  3. A small nonpolar hydrogen (the hydrogen at C5 of cytosine), a hydrogen-bond donor (the exocyclic amino group on C4 of cytosine), a hydrogen-bond acceptor (the carbonyl on C6 of guanine) and a hydrogen-bond acceptor (at N7 of guanine)

  4. A small nonpolar hydrogen (the hydrogen at C5 of cytosine), a hydrogen-bond acceptor (the exocyclic amino group on C4 of cytosine), a hydrogen-bond acceptor (the carbonyl on C6 of guanine) and a hydrogen-bond donor (at N7 of guanine)

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TLS Online TPP Program

#Question id: 4281

#Unit 3. Fundamental Processes

Proteins targeted to non-matrix regions of mitochondria

a. contain a matrix-targeting signal if the destination is the outer membrane.

b. utilize a stop-transfer signal if the destination is the outer membrane.

c. always contain a matrix-targeting signal if the destination is the intermembrane space.

d. may require a chaperone for transport.

e. always move first to the matrix and then to their final destination.

TLS Online TPP Program

#Question id: 4282

#Unit 3. Fundamental Processes

Which of the following protein(s) is (are) found in the peroxisome matrix?

TLS Online TPP Program

#Question id: 4283

#Unit 3. Fundamental Processes

Proteins can enter which organelle(s) in their folded conformation?

TLS Online TPP Program

#Question id: 4284

#Unit 3. Fundamental Processes

Assays for following the trafficking of proteins through the secretory pathway in living cells require

a. sensitive methods to distinguish the very small differences in organelle density caused by passage of a wave of protein transport through the organelle.

b. a way to identify compartments where labeled proteins are located.

c. the use of cell types that are highly dedicated secretory cells.

d. the use of enucleate cells in order to eliminate the nucleus as a site of labeling.

e. a way to label a cohort of secretory proteins

TLS Online TPP Program

#Question id: 4285

#Unit 3. Fundamental Processes

VSV G protein has been a very useful tracker protein for both living cell and in vitro assays because

TLS Online TPP Program

#Question id: 4286

#Unit 3. Fundamental Processes

Transport vesicles

a. can have a clathrin coat.     b. can be coated with a heteromeric COPI and COPII coat.

c. can contain assembly proteins.

d. can shuttle proteins from mitochondria to the endoplasmic reticulum.

e. can fuse with target organelles.