Which of the following statements regarding the Structural Maintenance Chromosomal proteins is correct?

A. The cohesins, along with a third protein, kleisin, are thought to form a ring around the replicated chromosomes.

B. Condensin binding causes the DNA to become underwound, in contrast to the overwinding induced by the binding of nucleosomes.

C. Cohesins are made up of pairs of Smc1 and Smc3 proteins, and condensins consist of Smc2-Smc4 pairs.

D. The primary structure of SMC proteins consists of three distinct domains.

#Question id: 4069

#Unit 3. Fundamental Processes

Which of the following can be identified using a series of promoter linker scanning mutations?

a. areas of the promoter that are non-essential

b. areas of the promoter that are essential

c. the presence of separate transcriptional control regions

d. spacing constraints on separate transcriptional control regions

#Question id: 4070

#Unit 3. Fundamental Processes

An enhancer

a. can be located upstream of a promoter.

b. can be located downstream of a promoter.

c. can be located a variable distance from the promoter.

d. is always located within 1 kb of the promoter.

e. can be cell-type-specific.

#Question id: 4071

#Unit 3. Fundamental Processes

The fact that a specific protein leaves a “footprint” on a DNA molecule is indicative of

a. a lack of interaction between the specific protein and DNA.

b. protection from DNAse by the specific protein.

c. binding of the specific protein to all types of DNA.

d. binding of the specific protein to a specific sequence of DNA.

#Question id: 4072

#Unit 3. Fundamental Processes

The C-terminal activation domain of transcriptional activators is capable of

a. binding to DNA. 

b. stimulating transcription.

c. interaction with other transcriptional machinery.

d. functioning in a fusion with a DNA-binding domain from an unrelated transcriptional activator.

#Question id: 4073

#Unit 3. Fundamental Processes

The expression of which gene(s) is (are) regulated by promoter proximal pausing?

#Question id: 4074

#Unit 3. Fundamental Processes

The promoter sequences of RNA polymerase III-transcribed genes are located