TLS Online TPP Program

#Question id: 2905


With respect to X-chromosome inactivation, which, if any, of the following statements are not correct? 

I. X-chromosome inactivation in mammals begins in the pre-implantation embryo 

II. In humans all diploid cells that carry two normal X-chromosomes are subject to a random pattern of X-inactivation. 

III. Once a decision has been made to inactivate an X chromosome (either the paternal or maternal X), all descendant cells show the same pattern of X-inactivation. 

IV. The inactivated X chromosome becomes a highly condensed Barr body in which genes are silenced across the length of the chromosome.

#Unit 2. Cellular Organization
  1. I and II

  2. I and III

  3. II and IV

  4. III and IV