Practice Questions

TLS Online TPP Program

#Question id: 2916

Which of the following statement is INCORRECT regarding the packaging of DNA into higher order chromatin structure?

#Unit 2. Cellular Organization

One of the two regions bound by H1 is the linker DNA at one end of the nucleosome. The second site of DNA binding is in the middle of the associated 147 bp (the only DNA duplex present at the dyad axis).
Core histones that had undergone nuclease treatment are capable of forming 30-nm fibers. The most likely role of the tails is to stabilize the 30-nm fiber by interacting with adjacent nucleosomes.
30-nm fiber forms loops of 40–90 kb that are held together at their bases by a proteinaceous structure referred to as the nuclear scaffold abundant in Topoisomerase-II and SMC proteins.
Positioning a nucleosome allows the DNA binding site for a regulatory protein to remain in the accessible linker DNA region as tightly positioned nucleosomes are most often found at sites directing the initiation of transcription.

More Questions

TLS Online TPP Program

#Question id: 22021

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following expression is correct for affinity of enzyme for substrate KmS for irreversible reaction

TLS Online TPP Program

#Question id: 22022

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following expression is correct for affinity of enzyme for product KmP for irreversible reaction

TLS Online TPP Program

#Question id: 22023

#Unit 1. Molecules and their Interaction Relevant to Biology

Choose the correct equation for Haldane reversible reaction

TLS Online TPP Program

#Question id: 22024

#Unit 1. Molecules and their Interaction Relevant to Biology

Some of the statements regarding competitive inhibition are given below

a) The effect of a competitive inhibitor depends on the inhibitor concentration, the substrate concentration and the relative affinities of the substrate and the inhibitor for the enzyme.

b) if the substrate concentration is low, the degree of inhibition will be great.

c) the substrate concentration is high, then the degree of inhibition will be marked low

d) non-competitive inhibitor can combine with an enzyme molecule to produce a dead-end complex

Choose the incorrect statement

TLS Online TPP Program

#Question id: 22025

#Unit 1. Molecules and their Interaction Relevant to Biology

The Lineweaver-Burk equation in the presence of a competitive inhibitor will be: and Lineweaver-Burk plot showing the effect of competitive inhibition are shown

What will be the value of X and X’ for above graph

TLS Online TPP Program

#Question id: 22060

#Unit 1. Molecules and their Interaction Relevant to Biology

Km can be calculated from two ways from Lineweaver-Burk equation, choose the most appropriate one