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TLS Online TPP Program

#Question id: 2916

Which of the following statement is INCORRECT regarding the packaging of DNA into higher order chromatin structure?

#Unit 2. Cellular Organization

  1. One of the two regions bound by H1 is the linker DNA at one end of the nucleosome. The second site of DNA binding is in the middle of the associated 147 bp (the only DNA duplex present at the dyad axis).

  2. Core histones that had undergone nuclease treatment are capable of forming 30-nm fibers. The most likely role of the tails is to stabilize the 30-nm fiber by interacting with adjacent nucleosomes.

  3. 30-nm fiber forms loops of 40–90 kb that are held together at their bases by a proteinaceous structure referred to as the nuclear scaffold abundant in Topoisomerase-II and SMC proteins.

  4. Positioning a nucleosome allows the DNA binding site for a regulatory protein to remain in the accessible linker DNA region as tightly positioned nucleosomes are most often found at sites directing the initiation of transcription.

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TLS Online TPP Program

#Question id: 409

#Unit 1. Molecules and their Interaction Relevant to Biology

For the following reaction,DG'° = +29.7 kJ/mol. L-Malate + NAD+ -> oxaloacetate + NADH + H+ The reaction as written:
TLS Online TPP Program

#Question id: 14481

#Unit 13. Methods in Biology

A card is drawn from an ordinary pack of playing cards and a person bets that it is a spade or an ace. Then the odds against his winning this bet is
TLS Online TPP Program

#Question id: 11167

#Unit 2. Cellular Organization

The core structure of the GPI group consists of :
TLS Online TPP Program

#Question id: 27561

#Unit 1. Molecules and their Interaction Relevant to Biology

Some proteins contain additional amino acids that arise by modification of an amino acid already present in a peptide, examples include
TLS Online TPP Program

#Question id: 27967

#Unit 1. Molecules and their Interaction Relevant to Biology

Malonate is an analog of succinate not normally present in cells, is a strong competitive inhibitor of succinate dehydrogenase, and its addition to mitochondria blocks the activity of the