TLS Online TPP Program

#Question id: 2973


Following statements are regarding to the spindle position checkpoint pathway in budding yeast.

A. During interphase and early mitosis, Cdc14 is sequestered and inactivated in the nucleolus. Inactive Tem1-GDP associates with the spindle pole body (SPB) nearest to the bud as soon as the mitotic spindle forms.

B. If chromosome segregation occurs properly, extension of the spindle microtubules inserts the daughter SPB into the bud, causing Tem1 to be activated by an unknown mechanism.

C. Tem1-GDP activates a protein kinase cascade, which then promotes the release of active Cdc14 from the nucleolus and exit from mitosis.

D. If the spindle apparatus fails to place the daughter SPB in the bud, Kin4 (cyan), an inhibitor of Tem1, is recruited from the parent cell cortex to the parent-cell-located SPB and maintains Tem1 in the GTP-bound form, and mitotic exit does not occur.

Which of the following are correct?

#Unit 2. Cellular Organization
  1. A, B and C

  2. A and B

  3. C and D

  4. D only

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TLS Online TPP Program

#Question id: 15408

#Unit 8. Inheritance Biology

Which of the following is not a protein or group of proteins required for conjugation to occur?

TLS Online TPP Program

#Question id: 15409

#Unit 8. Inheritance Biology

 A heterozygous trihybrid corn plant is testcrossed and the following progeny are produced (all traits are recessive to their wildtype alternative);
          booster                              6
          booster, silkless                  137       
          booster, liguleless, silkless      291
          liguleless                          142
          liguleless, silkless                  3
          silkless                            30
          booster, liguleless                  34
          wildtype                            339
What is the order of the loci on the chromosome? 

TLS Online TPP Program

#Question id: 15410

#Unit 8. Inheritance Biology

A pattern of transmission where all offspring have the same phenotype as their mother is consistent with which type of non-Mendelian inheritance?

TLS Online TPP Program

#Question id: 15411

#Unit 8. Inheritance Biology

Both X-linked genes and extranuclear inheritance produce different results in reciprocal crosses. How can you distinguish between them?

TLS Online TPP Program

#Question id: 15412

#Unit 8. Inheritance Biology

For a trait known to be caused by a mitochondrial gene variant, there may be an occasional female that can transmit different phenotypes to her progeny on an apparently random basis. What situation might you suspect?

TLS Online TPP Program

#Question id: 15413

#Unit 5. Developmental Biology

Paired box 6 (Pax6) transcription factor requires for :