TLS Online TPP Program

#Question id: 2977


The mitotic exit network that localizes to spindle pole bodies and whose activity is regulated by spindle position belongs to the family of signaling pathways known as the Hippo pathway in metazoans. Following statements are-

A. The conserved core of the Hippo signaling pathways consists of the Hippo protein kinase, which activates the Lats-Mob1 kinase.

B. The kinases are organized by a scaffolding molecule that, at least in budding and fission yeasts, targets the kinase cascade to centrosomes.

C. As in many kinase signaling cascades, a GTPase controls the activity of the mitotic exit network and the septation initiation network.

D. In metazoans, activation of the Hippo pathway leads to tissue overgrowth because the transcriptional activator TAZ (known as YAP in the mouse) constitutively promotes the expression of growth- and proliferation-promoting genes.

Which of the following statements are incorrect?

#Unit 2. Cellular Organization
  1. A and C

  2. B, C and D

  3. B only

  4. D only

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TLS Online TPP Program

#Question id: 31332

#Unit 5. Developmental Biology

When the epithelial cells and mesenchymal cells placed together, the same epithelium develops different structures according to the region from which the mesenchyme was taken, phenomena known as:

TLS Online TPP Program

#Question id: 31333

#Unit 5. Developmental Biology

According to the Quartet Model of flower development, the identity of each of the floral organs is determined by four combinations of the floral homeotic proteins. Match the following model of interaction with floral organs. 


TLS Online TPP Program

#Question id: 31334

#Unit 5. Developmental Biology

The regrowth of hair shafts from follicular stem cells in the hair bulge is an example of regeneration. Which is similar mechanism like:

TLS Online TPP Program

#Question id: 31335

#Unit 2. Cellular Organization

The following statements are made with reference to  SNARE proteins & membrane fusion reactions in vesicle transport. Which of the following statement is incorrect?

TLS Online TPP Program

#Question id: 31336

#Unit 1. Molecules and their Interaction Relevant to Biology

A peptide has the sequence Ala–His–Trp–Ser–Gly–Leu. What will the net charge of the molecule at pH 3&8

TLS Online TPP Program

#Question id: 31337

#Unit 1. Molecules and their Interaction Relevant to Biology

Ionic strength also profoundly influences protein solubility. Which of the following statement is incorrect according to the figure given.