TLS Online TPP Program

#Question id: 2978


The most important regulatory control that restricts cyclins to the appropriate cell cycle stage is ubiquitin mediated, proteasome-dependent protein degradation. Which of the following statement is incorrect regarding to the degradation of protein?

#Unit 2. Cellular Organization
  1. SCF and APC/C are multisubunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases which ensure that the cell cycle engine is driven forward and that cells cannot “go backward” in the cell cycle.

  2. SCF recognizes its substrates only when they are phosphorylated.

  3. The substrate specificity of active, dephosphorylated APC/C is determined in part by its association with one of two related substrate targeting factors called Cdc20 and Cdh1.

  4. The substrates of APC/C contain recognition motifs known as destruction box which is lysine rich.

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TLS Online TPP Program

#Question id: 3364

#Unit 11. Evolution and Behavior

Which of the following equations represents the corresponding equilibrium for a locus with three alleles p, q and r of diploid individuals? (P, Q and R represent the frequencies of p, q and r, respectively)

TLS Online TPP Program

#Question id: 3365

#Unit 11. Evolution and Behavior

Consider a population of 10,000 individuals, of which 2500 are homozygotes (PP) and 3000 are heterozygotes (Pp) genotype. The frequency of allele p in the population is

TLS Online TPP Program

#Question id: 3366

#Unit 11. Evolution and Behavior

Red-Green color blindness is an X-linked recessive disorder. In a population which is in the Hardy-  Weinberg equilibrium, the incidence of occurrence of this in males is 2:2000. What will be the expected incidence of affected homozygous females?

TLS Online TPP Program

#Question id: 3367

#Unit 11. Evolution and Behavior

The largest unit within which gene flow can readily occur is a

TLS Online TPP Program

#Question id: 3368

#Unit 11. Evolution and Behavior

The origin of a new plant species by hybridization, coupled with accidents during nuclear division, is an example of

TLS Online TPP Program

#Question id: 3369

#Unit 11. Evolution and Behavior

Genetic drift refers to random changes in allele frequencies over time leads to following consequence

a. Loss of genetic diversity per generation   

b. change in allelic frequency just by chance 

c. It caused adaptive evolution

d. It one allele may reach to 0 frequency