Following statements are regarding to the protein phosphatase Cdc14 function in budding yeast.

A. In budding yeast, the protein phosphatase Cdc14 throws the switch between two mutually antagonistic states during anaphase.

B. Cdc14 is kept inactive during most of the cell cycle, but is activated during anaphase by a GTPase signaling pathway known as the mitotic exit network.

C. Mitotic exit network is unresponsive to spindle position and becomes active in anaphase.

D. Cdc14 phosphatase activated by the activation of protein kinase cascade.

E. Cdc14 dephosphorylates APC/CCdh1 and Sic1 to promote mitotic cyclin degradation

and mitotic CDK inactivation, respectively. This process leads to exit from mitosis.

Which of the following combination is incorrect?

TLS Online TPP Program

#Question id: 24670

#Unit 2. Cellular Organization

Which of the following statement(s) is (are) true of V-class proton pumps?

a. They are ATPases.

b. They are present in membranes of plant vacuoles.

c. They serve to decrease the pH inside a lysosome.

d. They can acidify the lumen of an organelle (or the extracellular space) because these pumps are electrogenic

TLS Online TPP Program

#Question id: 24671

#Unit 2. Cellular Organization

Cholesterol and phospholipids are transported between organelles by

i. Golgi-dependent mechanisms.

ii. incompletely characterized vesicle populations.

iii. direct contact between membranes and, to some extent, small, soluble lipid-transfer proteins.

Which of the following statements are correct?

TLS Online TPP Program

#Question id: 24672

#Unit 2. Cellular Organization

Which statement describes the mode of action of the ABCB1 transporter (the first eukaryotic ABC transporter to be recognized)?

TLS Online TPP Program

#Question id: 24673

#Unit 2. Cellular Organization

Which of the following properties is (are) typical of uniport proteins?

TLS Online TPP Program

#Question id: 24674

#Unit 2. Cellular Organization

 Membrane lipids may

a. spontaneously flip-flop from one membrane leaflet to the other.

b. move laterally within one membrane leaflet.

c. aggregate with membrane proteins to form lipid rafts.

d. be unequally distributed in the two membrane leaflets.

e. be present in varying amounts in different cellular membranes

TLS Online TPP Program

#Question id: 26339

#Unit 2. Cellular Organization

According to fourth parity rule proposed by Erwin Chargaff which of the following statement are most appropriate