Cell cycle is regulated by master regulators (cyclin and CDKs). In vertebrates, G1 CDK activity rises during G1 and is stimulated by the presence of growth factors. When signaling from growth factors is sustained, the resulting cyclin D–CDK4/6 complexes begin phosphorylating Rb, releasing some E2F, which stimulates transcription of the genes encoding cyclin E, CDK2, and E2F itself. In a particular cell type there is a mutation in Rb such that it cannot be phosphorylated. What will be the correct expression pattern of cyclin E in these cells after mitotic stimulation?

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#Question id: 1492

#Unit 4. Cell Communication and Cell Signaling

Cancer is said to be monoclonal. What does that mean?

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#Question id: 23677

#Unit 13. Methods in Biology

Which of the following is not an application of PCR?

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#Question id: 15455

#Unit 4. Cell Communication and Cell Signaling

Variable region of antibody containing sequence motif DGYW/WRCH, which are responsible for mutation, where R, W, H represented as____

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#Question id: 1910

#Unit 4. Cell Communication and Cell Signaling

Hyperacute graft rejection is caused by:

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#Question id: 2172

#Unit 2. Cellular Organization

The osmotic potential of a hypotonic solution should cause an animal cell to _____, but with frog oocytes prevent this effect by _____.